Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19331718 | 0.86 | USP2 (0.38) | TSHRALDH1A1TRPA1ABCC4MAPT | |
| SCHEMBL19331610 | 0.86 | USP2 (0.38) | TSHRALDH1A1TRPA1ABCC4MAPT | |
| SCHEMBL25764311 | 0.86 | USP2 (0.38) | TSHRALDH1A1TRPA1ABCC4MAPT | |
| SCHEMBL28733941 | 0.78 | USP2 (0.39) | TSHRALDH1A1TRPA1ABCC4MAPT | |
| SCHEMBL5855326 | 0.75 | TSHR (0.55) | TSHRALDH1A1TRPA1 | |
| SCHEMBL5856184 | 0.75 | — | — | |
| SCHEMBL7284670 | 0.75 | TSHR (0.62) | TSHRALDH1A1TRPA1MAPTUSP2 | |
| SCHEMBL14855845 | 0.74 | — | — | |
| SCHEMBL15776014 | 0.74 | — | — | |
| SCHEMBL7279691 | 0.73 | TSHR (0.61) | TSHRALDH1A1MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161827-B2 | Catalytic systems for stereoselective synthesis of chiral amines by enantiodivergent radical C—H amination | THE TRUSTEES OF BOSTON COLLEGE (MA) | 2021-11-02 | — | — | US | disclosed |
| US-20200317627-A1 | CATALYTIC SYSTEMS FOR STEREOSELECTIVE SYNTHESIS OF CHIRAL AMINES BY ENANTIODIVERGENT RADICAL C-H AMINATION | TRUSTEES OF BOSTON COLLEGE (US) | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161827-B2 | Catalytic systems for stereoselective synthesis of chiral amines by enantiodivergent radical C—H amination | STS, SRM, SCLY | TSHR 2051/4885ALDH1A1 725/4885TRPA1 3562/4885 |
| US-20200317627-A1 | CATALYTIC SYSTEMS FOR STEREOSELECTIVE SYNTHESIS OF CHIRAL AMINES BY ENANTIODIVERGENT RADICAL C-H AMINATION | STS, SCLY, SRM | TSHR 2046/4885ALDH1A1 742/4885TRPA1 3636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.