Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966933 | 1.00 | HRH3 (0.55) | HRH3MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL15462867 | 1.00 | HRH3 (0.55) | HRH3MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL8023825 | 1.00 | — | — | |
| SCHEMBL19173238 | 1.00 | HRH3 (0.55) | HRH3MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL11712553 | 1.00 | HRH3 (0.55) | HRH3MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL12811 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL9592 | 0.97 | HRH3 (0.52) | HRH3MAPTALDH1A1POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL227556 | 0.97 | HRH3 (0.52) | HRH3MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL263561 | 0.97 | — | — | |
| Hypochlorous Acid SCHEMBL10439976 | 0.94 | HRH3 (0.50) | HRH3MAPTALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392411-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | Hovione Farmaciencia SA (PT) | 2024-07-03 | — | — | EP | claimed |
| CN-118159526-A | Process for preparing chloroalkyl substituted cyclic amines | 好利安药理股份公司 | 2024-06-07 | — | — | CN | claimed |
| WO-2023030667-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | HOVIONE SCIENTIA (IE) | 2023-03-09 | — | — | WO | claimed |
| CN-104693144-B | A kind of N-(2-chloroethyl) synthetic method of hexamethylene imine hydrochlorate | 山东川成医药股份有限公司 | 2016-08-24 | — | — | CN | claimed |
| US-20240383854-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | HOVIONE FARMACIENCIA SA (PT) | 2024-11-21 | — | — | US | disclosed |
| EP-4392411-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | Hovione Farmaciencia SA (PT) | 2024-07-03 | — | — | EP | disclosed |
| CN-118159526-A | Process for preparing chloroalkyl substituted cyclic amines | 好利安药理股份公司 | 2024-06-07 | — | — | CN | disclosed |
| US-20240067639-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | University of Florida Research Foundation, Incorporation (US) | 2024-02-29 | — | — | US | disclosed |
| US-20240067639-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | University of Florida Research Foundation, Incorporation (US) | 2024-02-29 | — | — | US | disclosed |
| US-11845751-B2 | Triazolotriazine derivatives as A2A receptor antagonists | ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD. (CN) | 2023-12-19 | — | — | US | disclosed |
| US-11845751-B2 | Triazolotriazine derivatives as A2A receptor antagonists | ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD. (CN) | 2023-12-19 | — | — | US | disclosed |
| EP-4210703-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | Expansion Therapeutics, Inc. (US) | 2023-07-19 | — | — | EP | disclosed |
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4107205-A | α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides and related compounds | G. D. SEARLE & CO. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4104380-A | Dibenzyl glycolic acid derivatives | WARNER-LAMBERT COMPANY (US) | 1978-08-01 | — | — | US | disclosed |
| US-4076937-A | Dibenzyl glycolic acid derivatives | WARNER-LAMBERT COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-4001229-A | ALKANESULFONAMIDO TRIPHENYLETHYLENES | MEAD JOHNSON & COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3962334-A | Aminoalkyl ethers of 2,2'- and 3,3'-dihydroxybenzil | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |
| US-3960886-A | Substituted N-arylanilines | STERLING DRUG INC. (US) | 1976-06-01 | — | — | US | disclosed |
| US-3935191-A | Aminoalkyl ethers of 2,2'- and 3,3'-dihydroxybenzil | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067639-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | FUS, SNRPE, RRBP1 | HRH3 1527/4885MAPT 349/4885ALDH1A1 4793/4885 |
| US-11845751-B2 | Triazolotriazine derivatives as A2A receptor antagonists | ADORA2A, ADORA1, ADORA3 | HRH3 416/4885MAPT 3868/4885ALDH1A1 571/4885 |
| US-20240383854-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | ETFB, TOP2B, MGMT | HRH3 1013/4885MAPT 4023/4885ALDH1A1 1381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.