SCHEMBL22497160

SCHEMBL22497160

NS(=O)(=O)c1ccn(CC(O)C(F)(F)F)n1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22497268 0.81 CSNK2A1 (0.34) —
SCHEMBL22497197 0.81 CSNK2A1 (0.34) —
SCHEMBL22497198 0.81 CSNK2A1 (0.34) —
SCHEMBL22497174 0.80 KDM4E (0.33) —
SCHEMBL22497203 0.80 KDM4E (0.33) —
SCHEMBL22497175 0.80 KDM4E (0.33) —
SCHEMBL23850759 0.80 LRRK2 (0.32) —
SCHEMBL21963207 0.76 CA12 (0.34) —
SCHEMBL23294063 0.72 CYP2D6 (0.32) KMT2A
SCHEMBL20757673 0.72 CYP2D6 (0.32) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12012392-B2 Sulfonamide carboxamide compounds INFLAZOME LIMITED (IE) 2024-06-18 — — US disclosed
US-20200317637-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LIMITED (IE) 2020-10-08 — — US disclosed
US-20200317637-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LIMITED (IE) 2020-10-08 — — US disclosed
CN-111315733-A Novel sulfonamide carboxamide compounds 英夫拉索姆有限公司 2020-06-19 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200317637-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS NLRP3, NOD1, PYCARD MEN1 4497/4885KMT2A 2404/4885
US-12012392-B2 Sulfonamide carboxamide compounds NLRP3, PYCARD, NOD1 MEN1 4261/4885KMT2A 2061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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