Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28262496 | 0.88 | LMNA (0.68) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7905955 | 0.87 | KMT2A (0.71) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11505600 | 0.87 | SMN1; SMN2 (0.70) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL111664 | 0.86 | LMNA (0.75) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11749290 | 0.86 | KMT2A (0.60) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27935114 | 0.84 | LMNA (0.58) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29035735 | 0.83 | ALDH1A1 (0.58) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23627035 | 0.82 | SMPD1 (0.67) | LMNAKMT2ATSHRADRB2ADRB1 | |
| SCHEMBL5165716 | 0.81 | LMNA (0.68) | LMNAALDH1A1KMT2ASMN1; SMN2ESR1 | |
| SCHEMBL28777000 | 0.81 | LMNA (0.68) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946240-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | Henkel AG & Co. KGaA (DE) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020200545-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | HENKEL AG & CO. KGAA (DE) | 2020-10-08 | — | — | WO | disclosed |