SCHEMBL22497935

SCHEMBL22497935

C[C@H](N)c1nccnc1Cl

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.34
PDCD1 Q15116 2/20 0.32
CD274 Q9NZQ7 2/20 0.32
NPC1 O15118 1/20 0.31
GAA P10253 1/20 0.31
RAB9A P51151 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
NFKB1 P19838 1/20 0.30
PNMT P11086 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6937966 1.00 ADRB2 (0.34) ADRB2PDCD1CD274NPC1GAA
SCHEMBL29434479 1.00 ADRB2 (0.34) ADRB2PDCD1CD274NPC1GAA
Hydrochloric Acid SCHEMBL22498583 0.98 NPC1 (0.33) ADRB2PDCD1CD274NPC1GAA
Hydrochloric Acid SCHEMBL21823105 0.98 NPC1 (0.33) ADRB2PDCD1CD274NPC1GAA
Hydrochloric Acid SCHEMBL29434551 0.98 NPC1 (0.33) ADRB2PDCD1CD274NPC1GAA
SCHEMBL2742982 0.80 CCNB2 (0.30)
SCHEMBL12335161 0.76
SCHEMBL22497968 0.76 DYRK1A (0.31) NPC1GAARAB9A
SCHEMBL30762127 0.76 DYRK1A (0.31) NPC1GAARAB9A
SCHEMBL6937377 0.76 DYRK1A (0.31) NPC1GAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12527325-B2 Pesticidally active diazine-amide compounds SYNGENTA CROP PROTECTION AG (CH) 2026-01-20 US disclosed
EP-3947358-B1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-06-18 EP disclosed
CN-113661165-B Pesticidally active diazine-amide compounds 先正达农作物保护股份公司 2025-05-23 CN disclosed
US-12281095-B2 Pesticidally active diazine-amide compounds SYNGENTA CROP PROTECTION AG (CH) 2025-04-22 US disclosed
CN-113631549-B Pesticidally active diazine-amide compounds 先正达农作物保护股份公司 2025-01-17 CN disclosed
US-20220289715-A1 PESTICIDALLY ACTIVE PYRAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-09-15 US disclosed
EP-4017851-A1 PESTICIDALLY ACTIVE PYRAZINE-AMIDE COMPOUNDS Syngenta Crop Protection AG (CH) 2022-06-29 EP disclosed
US-20220185789-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-06-16 US disclosed
US-20220185789-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-06-16 US disclosed
US-20220169629-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-06-02 US disclosed
CN-113661165-A Pesticidally active diazine-amide compounds 先正达农作物保护股份公司 2021-11-16 CN disclosed
CN-113631549-A Pesticidally active diazine-amide compounds 先正达农作物保护股份公司 2021-11-09 CN disclosed
WO-2021037614-A1 PESTICIDALLY ACTIVE PYRAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2021-03-04 WO disclosed
WO-2021037614-A1 PESTICIDALLY ACTIVE PYRAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2021-03-04 WO disclosed
WO-2020208036-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-10-15 WO disclosed
WO-2020208036-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-10-15 WO disclosed
WO-2020201079-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-10-08 WO disclosed
WO-2020201079-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-10-08 WO disclosed
WO-2020201398-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-10-08 WO disclosed
WO-2020201398-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527325-B2 Pesticidally active diazine-amide compounds DDT, CHRM1, C3AR1 ADRB2 640/4885PDCD1 3490/4885CD274 4132/4885
US-20220289715-A1 PESTICIDALLY ACTIVE PYRAZINE-AMIDE COMPOUNDS ACHE, DDT, NAT1 ADRB2 625/4885PDCD1 1075/4885CD274 3246/4885
US-20220185789-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS DDT, ACHE, NIT2 ADRB2 1033/4885PDCD1 348/4885CD274 1124/4885
US-12281095-B2 Pesticidally active diazine-amide compounds DDT, ACHE, NIT2 ADRB2 1033/4885PDCD1 348/4885CD274 1124/4885
US-20220169629-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS DDT, ACHE, NIT2 ADRB2 862/4885PDCD1 441/4885CD274 1541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.