SCHEMBL225025

SCHEMBL225025

C=CC(=O)OC(F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
TP53 P04637 3/20 0.35
HIF1A Q16665 3/20 0.35
CYP3A4 P08684 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TSHR P16473 6/20 0.34
HSD17B10 Q99714 1/20 0.34
HPGD P15428 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5091908 0.89 ALDH1A1 (0.32) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL17417861 0.87 THRB (0.32) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL225514 0.87 ALDH1A1 (0.31) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL2199662 0.85 THRB (0.35) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL4848426 0.85 THRB (0.35) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL14312168 0.85 THRB (0.35) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL4893028 0.85 THRB (0.35) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL223955 0.85 THRB (0.35) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL4885942 0.85 THRB (0.35) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL2196995 0.85 THRB (0.35) ALDH1A1TP53HIF1ACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 447 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12130531-B2 Composite electrophoretic particles and variable transmission films containing the same E INK CORPORATION (US) 2024-10-29 US claimed
CN-117913346-B Composite solid electrolyte and preparation method and application thereof 浙江大学 2024-08-16 CN claimed
CN-113330365-B Composite electrophoretic particles and variable transmission film containing same 伊英克公司 2024-07-30 CN claimed
CN-118325037-A Stain-resistant ultraviolet light-moisture mixed cured resin and preparation method thereof 深圳职业技术大学 2024-07-12 CN claimed
CN-117946303-A Catalyst, preparation method thereof, method for regulating and controlling ethylene polymerization kinetics behavior and application 中国石油化工股份有限公司 2024-04-30 CN claimed
CN-117913346-A Composite solid electrolyte and preparation method and application thereof 浙江大学 2024-04-19 CN claimed
CN-116622020-A Hydroxyl-containing acrylate structure compatibilizer and preparation method thereof 哈尔滨工业大学无锡新材料研究院 2023-08-22 CN claimed
US-20230148203-A1 COMPOSITE ELECTROPHORETIC PARTICLES AND VARIABLE TRANSMISSION FILMS CONTAINING THE SAME E INK CORPORATION 2023-05-11 US claimed
US-11567388-B2 Composite electrophoretic particles and variable transmission films containing the same E INK CORPORATION (US) 2023-01-31 US claimed
EP-3931632-A1 COMPOSITE ELECTROPHORETIC PARTICLES AND VARIABLE TRANSMISSION FILMS CONTAINING THE SAME E Ink Corporation (US) 2022-01-05 EP claimed
CN-113330365-A Composite electrophoretic particles and variable transmission film containing the same 伊英克公司 2021-08-31 CN claimed
US-20200272017-A1 COMPOSITE ELECTROPHORETIC PARTICLES AND VARIABLE TRANSMISSION FILMS CONTAINING THE SAME E INK CORPORATION 2020-08-27 US claimed
US-8648160-B2 Optical semiconductor sealing material IDEMITSU KOSAN CO., LTD. (JP) 2014-02-11 US claimed
US-8168704-B2 Adhesive composition and optical member including the same CHEIL INDUSTRIES, INC. (KR) 2012-05-01 US claimed
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME LIVING PROOF, INC. 2009-04-23 US claimed
US-20090053519-A1 Adhestive composition and optical member including the same Wuxi Hengxin Optoelectronic Materials Co., Ltd. (CN) 2009-02-26 US claimed
US-20040221943-A1 adhesive bonding of an endless seamed flexible belt such as intermediate transfer belt using an adhesive coating of a polylactam and a release substrate such as ethylene-chlorotrifluoroethylene copolymer; adhesive strip melts and flows between the mutually mating members of the seam XEROX CORPORATION 2004-11-11 US claimed
US-20040221942-A1 adhesive bonding of an photoreceptor belt using an adhesive coating of a polylactam and a release substrate such as polypropylene; adhesive strip melts and flows between the mutually mating members of the seam XEROX CORPORATION 2004-11-11 US claimed
CN-122026007-A Separator and battery 惠州亿纬锂能股份有限公司 2026-05-12 CN disclosed
US-3998620-A DEESTERIFICATION OF A FLUORINATED ACRYLIC ESTER POLYMER BY WATER AFFORDING HERBICIDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME TET1, TET2, TET3 ALDH1A1 457/4885TP53 879/4885HIF1A 624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.