SCHEMBL22503287

SCHEMBL22503287

O=C(O)C1CC=CCC1C(=O)NS(=O)(=O)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.46
POLB P06746 6/20 0.45
TDP1 Q9NUW8 4/20 0.45
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 1/20 0.45
GAA P10253 2/20 0.43
GRM4 Q14833 1/20 0.43
TSHR P16473 2/20 0.42
HSD17B10 Q99714 1/20 0.42
HTT P42858 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22503289 0.83 CA1 (0.39) SMN1; SMN2POLBTDP1ALDH1A1KDM4E
SCHEMBL26163050 0.78 ALDH1A1 (0.44) SMN1; SMN2POLBALDH1A1KDM4EGAA
SCHEMBL60588 0.71 POLB (0.54) SMN1; SMN2POLBTDP1ALDH1A1KDM4E
SCHEMBL14433706 0.71 POLB (0.54) SMN1; SMN2POLBTDP1ALDH1A1KDM4E
SCHEMBL10739509 0.71 POLB (0.54) SMN1; SMN2POLBTDP1ALDH1A1KDM4E
SCHEMBL10739512 0.71 POLB (0.54) SMN1; SMN2POLBTDP1ALDH1A1KDM4E
SCHEMBL31737192 0.71 POLB (0.54) SMN1; SMN2POLBTDP1ALDH1A1KDM4E
SCHEMBL174303 0.71 POLB (0.54) SMN1; SMN2POLBTDP1ALDH1A1KDM4E
SCHEMBL7864425 0.70 POLB (0.56) SMN1; SMN2POLBTDP1ALDH1A1KDM4E
SCHEMBL19810864 0.69 CA1 (0.50) SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230161252-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-20230161252-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-10792489-B2 Bio-electrode composition, bio-electrode, and method for manufacturing the bio-electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-10-06 US disclosed