Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 17/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20444247 | 1.00 | FFAR1 (0.42) | FFAR1SIRT6CYP2C8CYP2C9 | |
| SCHEMBL20398724 | 1.00 | FFAR1 (0.42) | FFAR1SIRT6CYP2C8CYP2C9 | |
| SCHEMBL28998297 | 1.00 | FFAR1 (0.42) | FFAR1SIRT6CYP2C8CYP2C9 | |
| SCHEMBL30123027 | 1.00 | FFAR1 (0.42) | FFAR1SIRT6CYP2C8CYP2C9 | |
| SCHEMBL28904056 | 1.00 | FFAR1 (0.42) | FFAR1SIRT6CYP2C8CYP2C9 | |
| SCHEMBL30239716 | 0.83 | FFAR1 (0.40) | FFAR1CYP2C8CYP2C9 | |
| SCHEMBL23543046 | 0.82 | FFAR1 (0.42) | FFAR1CYP2C8CYP2C9 | |
| SCHEMBL28960305 | 0.82 | FFAR1 (0.39) | FFAR1CYP2C8 | |
| SCHEMBL20398738 | 0.81 | FFAR1 (0.38) | FFAR1CYP2C8 | |
| SCHEMBL20398739 | 0.81 | FFAR1 (0.38) | FFAR1CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793530-B2 | Benzylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793530-B2 | Benzylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof | GPR119, GPR65, GPR52 | FFAR1 13/4885SIRT6 1733/4885CYP2C8 1709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.