Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29240283 | 1.00 | PRSS1 (0.51) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL6383536 | 1.00 | PRSS1 (0.51) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL20381899 | 0.98 | TSHR (0.51) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL14716467 | 0.98 | PRSS1 (0.50) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL14716431 | 0.98 | PRSS1 (0.50) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL14716407 | 0.98 | PRSS1 (0.50) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL14716299 | 0.96 | TSHR (0.50) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL20815546 | 0.94 | TSHR (0.47) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL7200750 | 0.89 | TSHR (0.47) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL28656958 | 0.88 | CYP3A4 (0.53) | PRSS1PRSS2PRSS3TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357133-A1 | NANOMATERIALS COMPRISING CARBONATES | BEAM THERAPEUTICS INC. | 2023-11-09 | — | — | US | disclosed |
| US-11344555-B2 | Nucleotide analogs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-05-31 | — | — | US | disclosed |
| US-20200316076-A1 | Nucleotide Analogs | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200316076-A1 | Nucleotide Analogs | NUDT1, DUT, DPYD | PRSS1 3432/4885PRSS2 3954/4885PRSS3 4016/4885 |
| US-20230357133-A1 | NANOMATERIALS COMPRISING CARBONATES | PHOSPHO1, CA13, SGMS2 | PRSS1 4105/4885PRSS2 4244/4885PRSS3 3844/4885 |
| US-11344555-B2 | Nucleotide analogs | NUDT1, DUT, DPYD | PRSS1 3432/4885PRSS2 3954/4885PRSS3 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.