SCHEMBL2250601

SCHEMBL2250601

Nc1nc(Cl)nc(-c2ccccc2)n1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 5/20 0.72
ADORA1 P30542 5/20 0.72
ADORA3 P0DMS8 2/20 0.72
ADORA2B P29275 2/20 0.72
POLB P06746 1/20 0.72
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
HTT P42858 1/20 0.59
ALDH1A1 P00352 3/20 0.55
HPGD P15428 3/20 0.55
LMNA P02545 3/20 0.55
KDM4E B2RXH2 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
GLA P06280 1/20 0.55
HSP90AA1 P07900 2/20 0.55
HSP90AB1 P08238 2/20 0.55
ALOX15 P16050 1/20 0.53
TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30205277 1.00 ADORA2A (0.72) ADORA2AADORA1ADORA3ADORA2BPOLB
SCHEMBL6986219 0.96 ADORA1 (0.67) ADORA2AADORA1ADORA3ADORA2BPOLB
SCHEMBL28243450 0.84 L3MBTL1 (0.58) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL27898 0.84 ADORA2A (1.00) ADORA2AADORA1ADORA3ADORA2BPOLB
Ammonia Solution, Strong SCHEMBL28043947 0.84 MEN1 (0.58) ADORA2AADORA1ADORA3ADORA2BPOLB
SCHEMBL782301 0.84 MEN1 (0.58) ADORA2AADORA1ADORA3ADORA2BPOLB
SCHEMBL18557130 0.84 MEN1 (0.58) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL28634836 0.84 ADORA2A (1.00) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL917182 0.84 ADORA2A (1.00) ADORA2AADORA1ADORA3ADORA2BPOLB
SCHEMBL106948 0.84 L3MBTL1 (0.58) ADORA2AADORA1ADORA3ADORA2BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111377932-B Compound, application thereof and organic electroluminescent device 北京鼎材科技有限公司 2023-08-22 CN disclosed
US-11566168-B1 Biocide blend for treating wellbores HALLIBURTON ENERGY SERVICES, INC. (US) 2023-01-31 US disclosed
US-20230026695-A1 BIOCIDE BLEND FOR TREATING WELLBORES HALLIBURTON ENERGY SERVICES, INC. 2023-01-26 US disclosed
WO-2023287453-A1 BIOCIDE BLEND FOR TREATING WELLBORES HALLIBURTON ENERGY SERVICES, INC. (US) 2023-01-19 WO disclosed
CN-111377932-A Compound, application thereof and organic electroluminescent device 北京鼎材科技有限公司 2020-07-07 CN disclosed
WO-2015155129-A1 DIAMINOTRIAZINE COMPOUND BASF SE (DE) 2015-10-15 WO disclosed
EP-2762483-A1 ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL HAVING SILICON-CONTAINING FOUR MEMBERED RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2014-08-06 EP disclosed
US-20140203270-A1 ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL HAVING SILICON-CONTAINING FOUR MEMBERED RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-07-24 US disclosed
US-20140203270-A1 ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL HAVING SILICON-CONTAINING FOUR MEMBERED RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-07-24 US disclosed
US-7989537-B2 Reduced formaldehyde emissions; safe for food and drink containers, toys, packaging, construction materials BASF AKTIENGESELLSCHAFT (DE) 2011-08-02 US disclosed
EP-1622974-B1 POLYOXYMETHYLENE MOLDING COMPOUNDS BASF AG (DE) 2006-07-26 EP disclosed
WO-2006074997-A1 MOULDING COMPOUND COMPRISING POLYOXYMETHYLENE AND ZEOLITE BASF AKTIENGESELLSCHAFT (DE) 2006-07-20 WO disclosed
CN-1777647-A Polyoxymethylene molding compounds BASF AG (DE) 2006-05-24 CN disclosed
EP-1622974-A1 POLYOXYMETHYLENE MOLDING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2006-02-08 EP disclosed
WO-2004096910-A1 POLYOXYMETHYLENE MOLDING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2004-11-11 WO disclosed
WO-2004083293-A1 STABILIZED POLYOXYMETHYLENE MOLDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2004-09-30 WO disclosed
WO-2004083304-A1 STABILIZED POLYOXYMETHYLENE MOLDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2004-09-30 WO disclosed
US-6143888-A TREATING THE SUBSTRATE WITH A TRIAZINE BASED ULTRAVIOLET ABSORPTION COMPOUND TO INHIBIT THE EFFECT OF AN ANIONIC FLUORECENT WHITENING AGENT CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-11-07 US disclosed
EP-0912530-A2 USE OF TRIAZINE-BASED UVAs FOR USE AS QUENCHERS IN PAPER-MAKING PROCESSES Ciba SC Holding AG (CH) 1999-05-06 EP disclosed
WO-1997046541-A2 USE OF TRIAZINE-BASED UVAs FOR USE AS QUENCHERS IN PAPER-MAKING PROCESSES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230026695-A1 BIOCIDE BLEND FOR TREATING WELLBORES KAT2B, WEE2, OTUB1 ADORA2A 4204/4885ADORA1 4130/4885ADORA3 4558/4885
US-11566168-B1 Biocide blend for treating wellbores KAT2B, WEE2, OTUB1 ADORA2A 4204/4885ADORA1 4130/4885ADORA3 4558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.