Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.63 |
| ▸ | LIG3 | P49916 | 1/20 | 0.63 |
| ▸ | LIG4 | P49917 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22506412 | 0.83 | LIG1 (0.69) | LIG1LIG3LIG4CA2PTGS2 | |
| SCHEMBL13934092 | 0.70 | CA2 (0.88) | CA1CA2PTGS2PTGS1GRIN2D | |
| SCHEMBL11409395 | 0.70 | CA1 (0.62) | CA1CA2PTGS2PTGS1GRIN2D | |
| SCHEMBL11409392 | 0.70 | CA1 (0.62) | CA1CA2PTGS2PTGS1GRIN2D | |
| SCHEMBL11418984 | 0.69 | CA1 (0.58) | CA1CA2PTGS2PTGS1GRIN2D | |
| SCHEMBL11411393 | 0.69 | CA1 (0.65) | CA1CA2PTGS2PTGS1GRIN2D | |
| SCHEMBL11422967 | 0.69 | CA1 (0.61) | CA1CA2PTGS2PTGS1GRIN2D | |
| SCHEMBL11411395 | 0.69 | CA1 (0.65) | CA1CA2PTGS2PTGS1GRIN2D | |
| SCHEMBL11418985 | 0.69 | CA1 (0.58) | CA1CA2PTGS2PTGS1GRIN2D | |
| SCHEMBL11415365 | 0.68 | CA1 (0.56) | CA1CA2PTGS2PTGS1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162649-A1 | NOVEL NUCLEIC ACID MODIFIERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-05-26 | — | — | US | disclosed |
| WO-2020206036-A1 | NOVEL NUCLEIC ACID MODIFIER | THE BROAD INSTITUTE, INC. (US) | 2020-10-08 | — | — | WO | disclosed |