SCHEMBL22507145

SCHEMBL22507145

O=C(CCCl)OCCOCCOCCOc1ccc(C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.57
RARB P10826 4/20 0.56
HTT P42858 3/20 0.51
MAPK1 P28482 2/20 0.48
TSHR P16473 2/20 0.48
TP53 P04637 1/20 0.48
PLA2G4B P0C869 3/20 0.47
ALDH1A1 P00352 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
USP2 O75604 1/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
POLB P06746 1/20 0.45
APEX1 P27695 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NR4A2 P43354 2/20 0.43
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
NR4A1 P22736 1/20 0.43
NR4A3 Q92570 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2203739 0.88 HTT (0.61) PKMRARBHTTMAPK1TSHR
SCHEMBL7646875 0.88 HTT (0.66) PKMRARBHTTMAPK1TSHR
SCHEMBL1667037 0.87 HTT (0.68) PKMRARBHTTTSHRTP53
SCHEMBL13918671 0.84 PKM (0.78) PKMRARBHTTMAPK1TSHR
SCHEMBL20502046 0.84 PKM (0.78) PKMRARBHTTMAPK1TSHR
SCHEMBL4509186 0.84 PKM (0.78) PKMRARBHTTMAPK1TSHR
SCHEMBL577687 0.84 PKM (0.78) PKMRARBHTTMAPK1TSHR
SCHEMBL15582454 0.83 RARB (0.63) PKMRARBHTTTSHRTP53
SCHEMBL3685290 0.82 GAA (0.60) PKMHTTMAPK1ALDH1A1L3MBTL1
SCHEMBL22525345 0.80 RARB (0.64) PKMRARBHTTMAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11697770-B2 Liquid crystal composition, method for producing high-molecular weight liquid crystal compound, light absorption anisotropic film, laminate, and image display device FUJIFILM CORPORATION (JP) 2023-07-11 US disclosed
US-11697770-B2 Liquid crystal composition, method for producing high-molecular weight liquid crystal compound, light absorption anisotropic film, laminate, and image display device FUJIFILM CORPORATION (JP) 2023-07-11 US disclosed
US-11578270-B2 Liquid crystalline composition, side chain type polymer liquid crystalline compound, light absorption anisotropic film, laminate, and image display device FUJIFILM CORPORATION (JP) 2023-02-14 US disclosed
US-11339329-B2 Polarizer and image display device FUJIFILM CORPORATION (JP) 2022-05-24 US disclosed
US-20210324272-A1 LIQUID CRYSTAL COMPOSITION, METHOD FOR PRODUCING HIGH-MOLECULAR WEIGHT LIQUID CRYSTAL COMPOUND, LIGHT ABSORPTION ANISOTROPIC FILM, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-10-21 US disclosed
US-20200347304-A1 LIQUID CRYSTALLINE COMPOSITION, SIDE CHAIN TYPE POLYMER LIQUID CRYSTALLINE COMPOUND, LIGHT ABSORPTION ANISOTROPIC FILM, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-11-05 US disclosed
US-20200318010-A1 POLARIZER AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-10-08 US disclosed