Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667037 | 0.98 | HTT (0.68) | HTTTP53TSHRPOLBAPEX1 | |
| SCHEMBL2203739 | 0.97 | HTT (0.61) | HTTTP53TSHRPOLBAPEX1 | |
| SCHEMBL15582454 | 0.94 | RARB (0.63) | HTTTP53TSHRPOLBAPEX1 | |
| SCHEMBL22507145 | 0.88 | PKM (0.57) | HTTTP53TSHRPOLBAPEX1 | |
| SCHEMBL7646498 | 0.88 | HTT (0.50) | HTTTP53TSHRPOLBAPEX1 | |
| SCHEMBL7401721 | 0.87 | TP53 (0.69) | HTTTP53TSHRPOLBAPEX1 | |
| SCHEMBL4081685 | 0.86 | HTT (0.52) | HTTTP53TSHRPOLBAPEX1 | |
| SCHEMBL1798003 | 0.85 | TP53 (0.72) | HTTTP53TSHRPOLBAPEX1 | |
| SCHEMBL177170 | 0.85 | PKM (0.69) | HTTTP53TSHRPOLBAPEX1 | |
| SCHEMBL3562863 | 0.84 | HTT (0.47) | HTTTP53TSHRPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486338-B1 | Preparation of organosilicon compounds containing α, β-unsaturated carboxylic acids | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2002-11-26 | — | — | US | disclosed |