Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18257688 | 0.82 | DYRK1A (0.38) | CDK1CDK2ADORA2AADORA1CHEK1 | |
| SCHEMBL22736706 | 0.80 | CYP19A1 (0.39) | CDK2PI4KAPI4KBCHEK1AURKA | |
| SCHEMBL18471002 | 0.80 | CHEK1 (0.39) | CDK2PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL19009131 | 0.79 | SMN1; SMN2 (0.39) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL13074136 | 0.75 | CDK1 (0.54) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL16160615 | 0.70 | DHFR (0.41) | CDK2CHEK1AURKADAPK3JAK2 | |
| SCHEMBL24113799 | 0.69 | CDK1 (0.50) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL23660141 | 0.68 | CHEK1 (0.40) | CDK2CHEK1AURKADAPK3JAK2 | |
| SCHEMBL21257150 | 0.67 | CHEK1 (0.36) | CDK2CHEK1AURKADAPK3JAK2 | |
| SCHEMBL16940094 | 0.67 | CHEK1 (0.36) | CDK2CHEK1AURKADAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200316210-A1 | Cell-Penetrating Peptides For Antisense Delivery | SAREPTA THERAPEUTICS, INC. | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200316210-A1 | Cell-Penetrating Peptides For Antisense Delivery | MYOF, TNNC1, MTPN | CDK1 4637/4885CCNB1 3621/4885CCNE1 4742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.