Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22508832 | 0.84 | TSHR (0.36) | LMNAHSD17B10TSHR | |
| SCHEMBL20275215 | 0.83 | PRMT1 (0.44) | PRMT1 | |
| SCHEMBL22508837 | 0.82 | LMNA (0.41) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL22508707 | 0.80 | LMNA (0.39) | LMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL16446954 | 0.80 | NOS2 (0.44) | — | |
| SCHEMBL17852276 | 0.80 | NOS2 (0.44) | — | |
| SCHEMBL28260909 | 0.80 | NOS2 (0.44) | — | |
| SCHEMBL20275376 | 0.73 | PHF8 (0.40) | LMNAKMT2ATSHRFOLH1 | |
| SCHEMBL22508720 | 0.71 | KMT2A (0.47) | LMNAKMT2AHSD17B10TDP1PRMT1 | |
| SCHEMBL20275340 | 0.70 | TSHR (0.44) | LMNAKMT2APRMT1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030545-B1 | AMINO ACID DERIVATIVES | MEDIMMUNE LTD (GB) | 2020-10-07 | — | — | EP | disclosed |