Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 7/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20275378 | 0.85 | ACHE (0.37) | LMNAEPHX2ACHEHTT | |
| SCHEMBL17852379 | 0.82 | NOS2 (0.41) | — | |
| SCHEMBL17840976 | 0.82 | NOS2 (0.41) | — | |
| SCHEMBL19513165 | 0.80 | EPHX2 (0.51) | KMT2AEPHX2ACHEHTT | |
| SCHEMBL22508746 | 0.80 | ACHE (0.37) | LMNAEPHX2ACHEHTT | |
| SCHEMBL22508698 | 0.80 | LMNA (0.44) | LMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL20275343 | 0.79 | ACHE (0.37) | EPHX2ACHEHTT | |
| SCHEMBL22508837 | 0.77 | LMNA (0.41) | LMNAKMT2AHSD17B10TDP1EPHX2 | |
| SCHEMBL15618153 | 0.74 | EPHX2 (0.51) | KMT2AEPHX2ACHEHTT | |
| SCHEMBL22508699 | 0.74 | SMN1; SMN2 (0.40) | LMNAEPHX2ACHEHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030545-B1 | AMINO ACID DERIVATIVES | MEDIMMUNE LTD (GB) | 2020-10-07 | — | — | EP | disclosed |