Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3571123 | 0.81 | STAT3 (0.43) | TRPV3HTTALDH1A1MAPTL3MBTL1 | |
| SCHEMBL22508787 | 0.76 | TAAR1 (0.43) | L3MBTL1MAOB | |
| SCHEMBL22508738 | 0.75 | PNMT (0.48) | ALDH1A1MAPTKCNH2 | |
| SCHEMBL30986331 | 0.74 | ALDH1A1 (0.52) | TRPV3HTTALDH1A1MAPTDAO | |
| SCHEMBL1238835 | 0.74 | ALDH1A1 (0.52) | TRPV3HTTALDH1A1MAPTDAO | |
| SCHEMBL16105820 | 0.73 | DAO (0.55) | TRPV3HTTALDH1A1DAOMAOA | |
| SCHEMBL12436729 | 0.73 | ALDH1A1 (0.45) | TRPV3HTTALDH1A1MAPTL3MBTL1 | |
| SCHEMBL8399619 | 0.71 | TDP1 (0.50) | ALDH1A1DPP4KCNH2MAOAMAOB | |
| SCHEMBL80635 | 0.71 | HTT (0.46) | TRPV3HTTALDH1A1MAPTDAO | |
| SCHEMBL16266018 | 0.71 | TDP1 (0.50) | ALDH1A1DPP4KCNH2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020206308-A1 | SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2020-10-08 | — | — | WO | disclosed |