Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16314688 | 0.82 | TAAR1 (0.45) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11462575 | 0.82 | TAAR1 (0.45) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL22508738 | 0.79 | PNMT (0.48) | TAAR1IGF1RALOX15IDO1 | |
| SCHEMBL8399619 | 0.79 | TDP1 (0.50) | ALOX15MAOBSLC6A4 | |
| SCHEMBL16266018 | 0.79 | TDP1 (0.50) | ALOX15MAOBSLC6A4 | |
| SCHEMBL11062642 | 0.79 | TAAR1 (0.50) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL16250318 | 0.76 | HTR3E (0.44) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL18704005 | 0.76 | SLC6A4 (0.52) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL22508798 | 0.76 | TRPV3 (0.39) | MAOBL3MBTL1 | |
| SCHEMBL4070796 | 0.75 | TAAR1 (0.52) | TAAR1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020206308-A1 | SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2020-10-08 | — | — | WO | disclosed |