Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18665117 | 0.91 | ALDH1A1 (0.40) | DNM1DGKAMAPTMAPK1RECQL | |
| SCHEMBL18789580 | 0.86 | DNM1 (0.48) | DNM1DGKAMAPTMAPK1RECQL | |
| SCHEMBL29974086 | 0.82 | DNM1 (0.44) | DNM1DGKAMAPTMAPK1RECQL | |
| SCHEMBL20589883 | 0.79 | DGKA (0.69) | DNM1DGKAMAPTPRSS1PRSS2 | |
| SCHEMBL18641652 | 0.78 | ALDH1A1 (0.43) | DNM1DGKAMAPTMAPK1RECQL | |
| SCHEMBL18971312 | 0.76 | DGKA (0.65) | DNM1DGKAMAPTPRSS1PRSS2 | |
| SCHEMBL31632750 | 0.76 | DGKA (0.56) | DNM1DGKAMAPTMAPK1RECQL | |
| SCHEMBL31632693 | 0.76 | DGKA (0.56) | DNM1DGKAMAPTMAPK1RECQL | |
| SCHEMBL31632743 | 0.76 | DGKA (0.56) | DNM1DGKAMAPTMAPK1RECQL | |
| SCHEMBL31632698 | 0.76 | DGKA (0.56) | DNM1DGKAMAPTMAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4011451-A1 | METAPNEUMOVIRUS MRNA VACCINES | ModernaTX, Inc. (US) | 2022-06-15 | — | — | EP | disclosed |
| EP-3458590-B9 | POLYNUCLEOTIDES ENCODING -GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE | MODERNATX INC (US) | 2021-08-18 | — | — | EP | disclosed |
| EP-3458590-B1 | POLYNUCLEOTIDES ENCODING -GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE | MODERNATX INC (US) | 2021-01-27 | — | — | EP | disclosed |
| EP-3718565-A1 | RESPIRATORY VIRUS VACCINES | ModernaTX, Inc. (US) | 2020-10-07 | — | — | EP | disclosed |