Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23023786 | 0.73 | PIK3CG (0.42) | KMT2AALDH1A1RAB9AATMKCNH2 | |
| SCHEMBL24278697 | 0.73 | TLR9 (0.36) | KMT2AALDH1A1RAB9AATMKCNH2 | |
| SCHEMBL22515493 | 0.70 | RAB9A (0.39) | KMT2AALDH1A1RAB9AATMKCNH2 | |
| SCHEMBL15290928 | 0.69 | RAB9A (0.59) | KMT2AALDH1A1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL21169197 | 0.67 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDTSHRLMNA | |
| SCHEMBL19203780 | 0.66 | KMT2A (0.51) | KMT2AALDH1A1RAB9AATMPOLB | |
| SCHEMBL25017779 | 0.65 | GRIN1 (0.30) | GRIN1GRIN2B | |
| SCHEMBL13856441 | 0.63 | NOTUM (0.42) | — | |
| SCHEMBL22600415 | 0.63 | NOTUM (0.42) | GRIN1GRIN2B | |
| SCHEMBL11325095 | 0.63 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2LMNAGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020205989-A1 | SMALL MOLECULE PROMOTING OSTEOBLAST DIFFERENTIATION | CORNELL UNIVERSITY (US) | 2020-10-08 | — | — | WO | disclosed |