⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31631820 | 0.88 | — | — | |
| SCHEMBL13058585 | 0.85 | — | — | |
| SCHEMBL17742617 | 0.82 | — | — | |
| SCHEMBL23967093 | 0.76 | — | — | |
| SCHEMBL15065650 | 0.76 | — | — | |
| SCHEMBL22543821 | 0.75 | LMNA (0.32) | — | |
| SCHEMBL14720754 | 0.75 | — | — | |
| SCHEMBL14720753 | 0.75 | — | — | |
| SCHEMBL24333441 | 0.73 | TRPV3 (0.33) | — | |
| SCHEMBL20606731 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230118115-A1 | SUBSTITUTED PYRAZOLO[3,4-d]PYRIMIDINES AS WEE1 INHIBITORS | INTEGRAL BIOSCIENCES PVT. LTD. (IN) | 2023-04-20 | — | — | US | disclosed |
| US-11332473-B2 | Substituted pyrazolo[3,4-d]pyrimidines as Wee1 inhibitors | NUVATION BIO INC. (US) | 2022-05-17 | — | — | US | disclosed |
| EP-3952877-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | Nuvation Bio Inc. (US) | 2022-02-16 | — | — | EP | disclosed |
| CN-113939296-A | Heterocyclic compounds and their use | 诺维逊生物股份有限公司 | 2022-01-14 | — | — | CN | disclosed |
| US-20200325142-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | SAGARD HOLDINGS MANAGER LP, AS ADMINISTRATIVE AGENT (CA) | 2020-10-15 | — | — | US | disclosed |
| WO-2020210375-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | NUVATION BIO INC. (US) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020210375-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | NUVATION BIO INC. (US) | 2020-10-15 | — | — | WO | disclosed |