⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22528538 | 0.88 | — | — | |
| SCHEMBL13058585 | 0.85 | — | — | |
| SCHEMBL17742617 | 0.82 | — | — | |
| SCHEMBL23967093 | 0.76 | — | — | |
| SCHEMBL15065650 | 0.76 | — | — | |
| SCHEMBL31631809 | 0.75 | NOS2 (0.35) | — | |
| SCHEMBL14720753 | 0.75 | — | — | |
| SCHEMBL14720754 | 0.75 | — | — | |
| SCHEMBL24333441 | 0.73 | TRPV3 (0.33) | — | |
| SCHEMBL20606730 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025125665-A1 | FURTHER SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | disclosed |