Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.60 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11232886 | 0.94 | CA4 (0.55) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL16341225 | 0.94 | CA4 (0.55) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL5159853 | 0.94 | CA4 (0.55) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL25 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1331273 | 0.94 | — | — | |
| Bicarbonate SCHEMBL97148 | 0.94 | — | — | |
| Bicarbonate SCHEMBL29061109 | 0.94 | CA4 (0.67) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL2121875 | 0.94 | CA4 (0.67) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL1331459 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28582066 | 0.94 | CA4 (0.67) | CA4FAHD1CA1MEN1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 746 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12527900-B2 | Sorbent bags | BASIONY MOHAMED A (US) | 2026-01-20 | — | — | US | claimed |
| CN-116328711-B | Inorganic adsorption material and preparation method and application thereof | 嘉兴高正新材料科技股份有限公司 | 2024-11-12 | — | — | CN | claimed |
| EP-1516884-B2 | Water-absorbent resin having treated surface and process for producing the same | NIPPON CATALYTIC CHEM IND (JP) | 2023-02-22 | — | — | EP | claimed |
| US-20230053271-A1 | Sorbent Bags | BASIONY MOHAMED A (US) | 2023-02-16 | — | — | US | claimed |
| EP-3730672-B1 | SURFACE TREATMENT SOLUTION COMPOSITION FOR TERNARY HOT-DIP ZINC ALLOY-PLATED STEEL SHEET, PROVIDING EXCELLENT CORROSION RESISTANCE AND BLACKENING RESISTANCE, TERNARY HOT-DIP ZINC ALLOY-PLATED STEEL SHEET SURFACE-TREATED USING SAME, AND MANUFACTURING METHOD THEREFOR | POSCO (KR) | 2022-11-16 | — | — | EP | claimed |
| EP-3730672-A1 | SURFACE TREATMENT SOLUTION COMPOSITION FOR TERNARY HOT-DIP ZINC ALLOY-PLATED STEEL SHEET, PROVIDING EXCELLENT CORROSION RESISTANCE AND BLACKENING RESISTANCE, TERNARY HOT-DIP ZINC ALLOY-PLATED STEEL SHEET SURFACE-TREATED USING SAME, AND MANUFACTURING METHOD THEREFOR | POSCO (KR) | 2020-10-28 | — | — | EP | claimed |
| CN-108689431-B | Preparation method of aqueous phase nano zirconium oxide particle dispersoid | 北京化工大学 | 2020-05-19 | — | — | CN | claimed |
| CN-108689431-A | A kind of preparation method of water phase nano zircite particle dispersion | 北京化工大学 | 2018-10-23 | — | — | CN | claimed |
| CN-108529674-A | A kind of preparation method of high dispersion nanometer oxide zirconium particle and its transparent dispersion | 北京化工大学 | 2018-09-14 | — | — | CN | claimed |
| CN-108486560-A | A kind of metal surface treating liquid and process of surface treatment | 苏州帝航防护设施有限公司 | 2018-09-04 | — | — | CN | claimed |
| US-20040022717-A1 | Heating a mixture of zirconium oxychloride and soda ash at a sufficient temperature and for a sufficient time to form sodium zirconium carbonate | WONG RAYMOND J (US) | 2004-02-05 | — | — | US | claimed |
| US-6627164-B1 | Heating zirconium oxychloride and soda ash | RENAL SOLUTIONS, INC. | 2003-09-30 | — | — | US | claimed |
| EP-1345687-A2 | CARTRIDGES USEFUL IN CLEANING DIALYSIS SOLUTIONS | Renal Solutions, Inc. (US) | 2003-09-24 | — | — | EP | claimed |
| EP-1345856-A2 | SODIUM ZIRCONIUM CARBONATE AND ZIRCONIUM BASIC CARBONATE AND METHODS OF MAKING THE SAME | Southern Ionics Incorporated (US) | 2003-09-24 | — | — | EP | claimed |
| US-20020112609-A1 | Sorbent cartridge comprising at least sodium zirconium carbonate | RENAL SOLUTIONS, INC. | 2002-08-22 | — | — | US | claimed |
| WO-2002044086-A2 | SODIUM ZIRCONIUM CARBONATE AND ZIRCONIUM BASIC CARBONATE AND METHODS OF MAKING THE SAME | RENAL SOLUTIONS, INC. (US) | 2002-06-06 | — | — | WO | claimed |
| WO-2002043859-A2 | CARTRIDGES USEFUL IN CLEANING DIALYSIS SOLUTIONS | RENAL SOLUTIONS INC (US) | 2002-06-06 | — | — | WO | claimed |
| US-6113989-A | Aqueous paint additive for staining inhibition and procedures | WAYNE PIGMENT CORP. (US) | 2000-09-05 | — | — | US | claimed |
| US-5789350-A | Compositions and processes for treating hydrocarbon-bearing formations | PHILLIPS PETROLEUM COMPANY (US) | 1998-08-04 | — | — | US | claimed |
| WO-1998029489-A1 | AQUEOUS PAINT ADDITIVE FOR STAINING INHIBITION AND PROCEDURE | WAYNE PIGMENT CORP. (US) | 1998-07-09 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12527900-B2 | Sorbent bags | SLC39A3, FGF23, SLC14A1 | CA4 528/4885FAHD1 2590/4885CA1 521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.