Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22529599 | 1.00 | ACACB (0.42) | ACACBPDE4APDE4DPARP15PARP10 | |
| SCHEMBL16612737 | 0.80 | MEN1 (0.39) | ACACBPARP15PARP10SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9111977 | 0.79 | MEN1 (0.39) | ACACBPARP15PARP10SLC6A2SLC6A4 | |
| SCHEMBL22546227 | 0.79 | PDE4A (0.49) | PDE4APDE4DPARP15PARP10SLC6A2 | |
| SCHEMBL22529648 | 0.77 | CYP2C9 (0.47) | PARP15PARP10SLC6A2SLC6A4HTR3A | |
| SCHEMBL9113516 | 0.76 | ACACB (0.40) | ACACBPARP15PARP10 | |
| SCHEMBL22546439 | 0.76 | PDE4A (0.44) | PDE4APDE4DPARP15PARP10SLC6A2 | |
| SCHEMBL22546277 | 0.74 | LMNA (0.50) | PDE4APDE4D | |
| SCHEMBL19849057 | 0.73 | ACACA (0.54) | ACACB | |
| SCHEMBL2551529 | 0.72 | ACACB (0.43) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020207611-A1 | PHENAZINES AS INHIBITORS OF DISCOIDIN DOMAIN RECEPTORS 2 (DDR2) | ROTTAPHARM BIOTECH S.R.L. (IT) | 2020-10-15 | — | — | WO | claimed |
| WO-2020207570-A1 | PHENAZINES AS INHIBITORS OF DISCOIDIN DOMAIN RECEPTORS 2 (DDR2) | ROTTAPHARM BIOTECH S.R.L. (IT) | 2020-10-15 | — | — | WO | claimed |
| WO-2020207570-A1 | PHENAZINES AS INHIBITORS OF DISCOIDIN DOMAIN RECEPTORS 2 (DDR2) | ROTTAPHARM BIOTECH S.R.L. (IT) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020207611-A1 | PHENAZINES AS INHIBITORS OF DISCOIDIN DOMAIN RECEPTORS 2 (DDR2) | ROTTAPHARM BIOTECH S.R.L. (IT) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020207611-A1 | PHENAZINES AS INHIBITORS OF DISCOIDIN DOMAIN RECEPTORS 2 (DDR2) | ROTTAPHARM BIOTECH S.R.L. (IT) | 2020-10-15 | — | — | WO | disclosed |