Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22533334 | 0.83 | SMN1; SMN2 (0.71) | WEE1PDE4DTP53SMN1; SMN2MAPT | |
| SCHEMBL22533527 | 0.78 | MAPT (0.59) | WEE1PDE4DTP53SMN1; SMN2MAPT | |
| SCHEMBL19079736 | 0.73 | PDE4D (0.68) | WEE1PDE4DTP53SMN1; SMN2MAPT | |
| SCHEMBL19079788 | 0.72 | L3MBTL1 (0.77) | PDE4DTP53SMN1; SMN2MAPTKDM4E | |
| SCHEMBL19079783 | 0.72 | PDE4D (0.80) | PDE4DTP53SMN1; SMN2MAPTKDM4E | |
| SCHEMBL22533075 | 0.72 | ALDH1A1 (0.45) | TP53SMN1; SMN2MAPTKDM4EL3MBTL1 | |
| SCHEMBL19079786 | 0.70 | PDE4D (0.72) | PDE4DTP53SMN1; SMN2MAPTKDM4E | |
| SCHEMBL19079698 | 0.70 | PDE4D (1.00) | PDE4DTP53SMN1; SMN2MAPTKDM4E | |
| SCHEMBL19079669 | 0.69 | SMN1; SMN2 (0.76) | PDE4DTP53SMN1; SMN2MAPTKDM4E | |
| SCHEMBL19079747 | 0.68 | KDM4E (0.75) | WEE1PDE4DTP53SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020210582-A1 | ALLOSTERIC AGONISTS AND POSITIVE ALLOSTERIC MODULATORS OF GLUCAGON-LIKE PEPTIDE 1 RECEPTOR | UNIVERSITY OF THE SCIENCES (US) | 2020-10-15 | — | — | WO | disclosed |