Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.71 |
| ▸ | WEE1 | P30291 | 1/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19079783 | 0.86 | PDE4D (0.80) | SMN1; SMN2TP53PDE4DABCB1KDM4E | |
| SCHEMBL19079736 | 0.85 | PDE4D (0.68) | SMN1; SMN2TP53PDE4DWEE1ABCB1 | |
| SCHEMBL19079788 | 0.84 | L3MBTL1 (0.77) | SMN1; SMN2TP53PDE4DABCB1KDM4E | |
| SCHEMBL19079669 | 0.84 | SMN1; SMN2 (0.76) | SMN1; SMN2TP53PDE4DABCB1KDM4E | |
| SCHEMBL19079698 | 0.83 | PDE4D (1.00) | SMN1; SMN2TP53PDE4DABCB1KDM4E | |
| SCHEMBL22533299 | 0.83 | WEE1 (0.58) | SMN1; SMN2TP53PDE4DWEE1ABCB1 | |
| SCHEMBL19079786 | 0.81 | PDE4D (0.72) | SMN1; SMN2TP53PDE4DABCB1KDM4E | |
| SCHEMBL19079713 | 0.79 | SMN1; SMN2 (0.69) | SMN1; SMN2TP53PDE4DKDM4EMEN1 | |
| SCHEMBL19079702 | 0.79 | PDE4D (0.90) | SMN1; SMN2TP53PDE4DABCB1KDM4E | |
| SCHEMBL19079787 | 0.78 | RXFP1 (0.62) | SMN1; SMN2TP53PDE4DKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220193080-A1 | ALLOSTERIC AGONISTS AND POSITIVE ALLOSTERIC MODULATORS OF GLUCAGON-LIKE PEPTIDE 1 RECEPTOR | UNIVERSITY OF THE SCIENCES (US) | 2022-06-23 | — | — | US | claimed |
| WO-2020210582-A1 | ALLOSTERIC AGONISTS AND POSITIVE ALLOSTERIC MODULATORS OF GLUCAGON-LIKE PEPTIDE 1 RECEPTOR | UNIVERSITY OF THE SCIENCES (US) | 2020-10-15 | — | — | WO | claimed |
| US-20220193080-A1 | ALLOSTERIC AGONISTS AND POSITIVE ALLOSTERIC MODULATORS OF GLUCAGON-LIKE PEPTIDE 1 RECEPTOR | UNIVERSITY OF THE SCIENCES (US) | 2022-06-23 | — | — | US | disclosed |
| US-20220193080-A1 | ALLOSTERIC AGONISTS AND POSITIVE ALLOSTERIC MODULATORS OF GLUCAGON-LIKE PEPTIDE 1 RECEPTOR | UNIVERSITY OF THE SCIENCES (US) | 2022-06-23 | — | — | US | disclosed |
| WO-2020210582-A1 | ALLOSTERIC AGONISTS AND POSITIVE ALLOSTERIC MODULATORS OF GLUCAGON-LIKE PEPTIDE 1 RECEPTOR | UNIVERSITY OF THE SCIENCES (US) | 2020-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220193080-A1 | ALLOSTERIC AGONISTS AND POSITIVE ALLOSTERIC MODULATORS OF GLUCAGON-LIKE PEPTIDE 1 RECEPTOR | GLP1R, GPR119, GIPR | SMN1; SMN2 3710/4885TP53 3522/4885PDE4D 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.