Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9899819 | 0.79 | P2RX7 (0.33) | — | |
| SCHEMBL13270562 | 0.73 | ALOX5AP (0.36) | — | |
| SCHEMBL2046063 | 0.72 | — | — | |
| SCHEMBL10711669 | 0.70 | LTA4H (0.46) | — | |
| SCHEMBL48962 | 0.69 | TAAR1 (0.35) | CCNE2CCNE1CDK2 | |
| SCHEMBL5535844 | 0.69 | CCNE2 (0.34) | CCNE2CCNE1CDK2 | |
| SCHEMBL15657546 | 0.68 | CCNE2 (0.33) | CCNE2CCNE1CDK2 | |
| SCHEMBL13634371 | 0.67 | — | — | |
| SCHEMBL680079 | 0.67 | — | — | |
| SCHEMBL13550174 | 0.67 | NOS3 (0.34) | CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020209933-A1 | IMPROVED INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX AND METHODS FOR USE OF THE SAME | UNIVERSITY OF MIAMI (US) | 2020-10-15 | — | — | WO | disclosed |