SCHEMBL22540964

SCHEMBL22540964

C=CC(=O)OCCOCCOC(=O)C(C)(C)C

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.70
ALDH1A1 P00352 5/20 0.70
TP53 P04637 3/20 0.70
HIF1A Q16665 3/20 0.70
HSD17B10 Q99714 1/20 0.70
THRB P10828 4/20 0.57
HPGD P15428 1/20 0.48
CYP3A4 P08684 2/20 0.48
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PRKCA P17252 1/20 0.33
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11682519 0.94 TSHR (0.59) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL17693804 0.87 TSHR (0.67) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL22540963 0.85 THRB (0.54) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL14617086 0.84 TSHR (0.63) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL12716859 0.84 TSHR (0.63) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL12701599 0.84 TSHR (1.00) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL8636795 0.84 TSHR (1.00) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL18134826 0.84 TSHR (1.00) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL4602612 0.84 TSHR (1.00) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL5021535 0.84 POLB (0.44) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873426-B2 Curable composition, cured product, optical member, lens, and compound FUJIFILM CORPORATION (JP) 2024-01-16 US disclosed
US-11518916-B2 Lens adhesive, cemented lens, and imaging module FUJIFILM CORPORATION (JP) 2022-12-06 US disclosed
US-20200325367-A1 LENS ADHESIVE, CEMENTED LENS, AND IMAGING MODULE FUJIFILM CORPORATION (JP) 2020-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200325367-A1 LENS ADHESIVE, CEMENTED LENS, AND IMAGING MODULE SP1, SPOP, SMC2 TSHR 3621/4885ALDH1A1 2380/4885TP53 1466/4885
US-11873426-B2 Curable composition, cured product, optical member, lens, and compound RB1, CCNO, SPOP TSHR 3973/4885ALDH1A1 2783/4885TP53 2376/4885
US-11518916-B2 Lens adhesive, cemented lens, and imaging module SP1, SPOP, SMC2 TSHR 3621/4885ALDH1A1 2380/4885TP53 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.