SCHEMBL22548522

SCHEMBL22548522

C1=Cc2cccc3c4cc5ccc6ccccc6c5cc4n(c23)-c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 3/20 0.46
HIF1A Q16665 1/20 0.46
CYP1B1 Q16678 1/20 0.46
P2RX4 Q99571 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
CYP1A2 P05177 3/20 0.37
HPGD P15428 1/20 0.37
CYP2A6 P11509 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
POLB P06746 1/20 0.33
ERBB2 P04626 1/20 0.33
FYN P06241 1/20 0.33
MAOA P21397 1/20 0.33
ACHE P22303 1/20 0.33
AHR P35869 1/20 0.33
HPRT1 P00492 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22548526 0.85 P2RX4 (0.34) ALDH1A1HSD17B10P2RX4TDP1CYP1A2
SCHEMBL22548525 0.71 P2RX4 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1P2RX4
SCHEMBL8780525 0.70 ALDH1A1 (0.57) ALDH1A1HSD17B10HIF1ACYP1B1TDP1
SCHEMBL26231981 0.70 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1TDP1
SCHEMBL16773282 0.69 ALDH1A1 (0.45) ALDH1A1HSD17B10HIF1ACYP1B1P2RX4
SCHEMBL22548524 0.69 P2RX4 (0.35) ALDH1A1P2RX4CYP1A2CYP2A6TSHR
SCHEMBL15073696 0.69 KDM4E (0.47) ALDH1A1HSD17B10HIF1ACYP1B1TDP1
SCHEMBL15821632 0.68 KDM4E (0.60) ALDH1A1HSD17B10HIF1ACYP1B1TDP1
SCHEMBL11797207 0.68 MAOA (0.41) ALDH1A1P2RX4POLBMAOAACHE
SCHEMBL15073610 0.68 KDM4E (0.42) ALDH1A1HSD17B10HIF1ACYP1B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020209514-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC LIGHT ELEMENT 덕산네오룩스 주식회사 2020-10-15 WO disclosed