Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24158177 | 0.76 | MEN1 (0.36) | MEN1KMT2AGAACYP1A2L3MBTL1 | |
| SCHEMBL22550304 | 0.72 | PAX8 (0.38) | MEN1KMT2A | |
| SCHEMBL21104440 | 0.72 | MEN1 (0.53) | MEN1KMT2AGAACYP1A2L3MBTL1 | |
| SCHEMBL22549892 | 0.70 | GAA (0.33) | MEN1KMT2AGAACYP1A2L3MBTL1 | |
| SCHEMBL24329565 | 0.70 | PNMT (0.33) | CYP1A2CYP1B1 | |
| SCHEMBL22579756 | 0.67 | EDNRB (0.38) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL3583212 | 0.66 | CYP1B1 (0.33) | CYP1A2CYP1B1 | |
| SCHEMBL17280555 | 0.64 | KDM1A (0.38) | CYP1A2CYP1B1 | |
| SCHEMBL23049948 | 0.64 | CYP1B1 (0.42) | MEN1KMT2ACYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL2679177 | 0.63 | CYP1A2 (0.45) | MEN1KMT2ACYP1A2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020210630-A1 | TRICYCLIC DEGRADERS OF IKAROS AND AIOLOS | C4 THERAPEUTICS, INC. (US) | 2020-10-15 | — | — | WO | disclosed |