Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16224765 | 0.76 | PARP1 (0.40) | CYP1A2 | |
| SCHEMBL24330025 | 0.72 | PNMT (0.45) | PNMTCYP1B1CYP1A2 | |
| SCHEMBL29583068 | 0.72 | PNMT (0.45) | PNMTCYP1B1CYP1A2 | |
| SCHEMBL22549751 | 0.70 | MEN1 (0.39) | CYP1B1CYP1A2 | |
| SCHEMBL3583212 | 0.70 | CYP1B1 (0.33) | PNMTCYP1B1CYP1A2 | |
| SCHEMBL359803 | 0.69 | CHRNB2 (0.44) | CYP1A2 | |
| SCHEMBL14395237 | 0.69 | CHRNB2 (0.44) | CYP1A2 | |
| SCHEMBL29568322 | 0.69 | CHRNB2 (0.44) | CYP1A2 | |
| Bromide SCHEMBL3966126 | 0.67 | CHRNB2 (0.42) | CYP1A2 | |
| Hydrochloric Acid SCHEMBL27585427 | 0.67 | MAPT (0.44) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081928-A1 | TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |