SCHEMBL22551452

SCHEMBL22551452

CO[SiH](OC)c1cc(C)ccc1S

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.35
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2A6 P11509 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22551442 0.79 CYP1A2 (0.32) CYP1A2
SCHEMBL3481714 0.72 KDM4E (0.37) ACHEALDH1A1CYP3A4CYP1A2
SCHEMBL8760067 0.71 TP53 (0.34) ACHE
SCHEMBL11304211 0.67 ACHE (0.62) ACHEALDH1A1CYP3A4CYP1A2
SCHEMBL29373274 0.66
SCHEMBL331198 0.66
Hydrochloric Acid SCHEMBL31606798 0.64 CYP2A6 (0.43) ACHEALDH1A1CYP3A4CYP1A2CYP2A6
SCHEMBL234687 0.64
SCHEMBL29511362 0.64
SCHEMBL30929155 0.64 CYP2A6 (0.43) ACHEALDH1A1CYP3A4CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111825710-B Alkoxysilyl group-containing organosilane compound, method for producing same, composition containing same, and cured product 信越化学工业株式会社 2024-08-23 CN disclosed
US-11739184-B2 Polysiloxazane compound having alkoxysilyl group, process for producing same, and composition and cured product including same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-29 US disclosed
US-11708460-B2 Alkoxysilyl group-containing organic silazane compound, method for producing same, composition containing same and cured product SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-25 US disclosed
EP-3798252-B1 POLYSILOXAZANE COMPOUND HAVING ALKOXYSILYL GROUP, PROCESS FOR PRODUCING SAME, AND COMPOSITION AND CURED PRODUCT INCLUDING SAME SHINETSU CHEMICAL CO (JP) 2022-06-29 EP disclosed
US-20210095079-A1 POLYSILOXAZANE COMPOUND HAVING ALKOXYSILYL GROUP, PROCESS FOR PRODUCING SAME, AND COMPOSITION AND CURED PRODUCT INCLUDING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-04-01 US disclosed
EP-3798252-A1 POLYSILOXAZANE COMPOUND HAVING ALKOXYSILYL GROUP, PROCESS FOR PRODUCING SAME, AND COMPOSITION AND CURED PRODUCT INCLUDING SAME Shin-Etsu Chemical Co., Ltd. (JP) 2021-03-31 EP disclosed
CN-111825710-A Organosilazane compounds containing alkoxysilyl groups, process for their preparation, compositions containing them and cured products 信越化学工业株式会社 2020-10-27 CN disclosed
US-20200332071-A1 ALKOXYSILYL GROUP-CONTAINING ORGANIC SILAZANE COMPOUND, METHOD FOR PRODUCING SAME, COMPOSITION CONTAINING SAME AND CURED PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-10-22 US disclosed
EP-3725822-A1 ALKOXYSILYL GROUP-CONTAINING ORGANIC SILAZANE COMPOUND, METHOD FOR PRODUCING SAME, COMPOSITION CONTAINING SAME AND CURED PRODUCT Shin-Etsu Chemical Co., Ltd. (JP) 2020-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708460-B2 Alkoxysilyl group-containing organic silazane compound, method for producing same, composition containing same and cured product OR10J3, ALKBH1, ALKBH2 ACHE 1377/4885ALDH1A1 197/4885CYP3A4 582/4885
US-20200332071-A1 ALKOXYSILYL GROUP-CONTAINING ORGANIC SILAZANE COMPOUND, METHOD FOR PRODUCING SAME, COMPOSITION CONTAINING SAME AND CURED PRODUCT OR10J3, ALKBH1, ALKBH2 ACHE 1377/4885ALDH1A1 197/4885CYP3A4 582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.