SCHEMBL225528

SCHEMBL225528

CCC(C)(c1cc(C(C)(C)C)c(O)cc1C)c1cc(C(C)(C)C)c(O)cc1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 5/20 0.52
ALDH1A1 P00352 5/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
CYP1A2 P05177 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MAPT P10636 1/20 0.52
ATP2A2 P16615 1/20 0.52
ATP2A3 Q93084 1/20 0.52
TP53 P04637 3/20 0.52
HIF1A Q16665 3/20 0.52
CYP3A4 P08684 2/20 0.52
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
MAPK1 P28482 1/20 0.52
CYP2C9 P11712 5/20 0.51
CYP2C19 P33261 4/20 0.51
CYP2D6 P10635 2/20 0.51
LMNA P02545 2/20 0.40
HPGD P15428 1/20 0.40
TYR P14679 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7018654 0.95 ALOX15 (0.47) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL16237184 0.85 ALOX15 (0.52) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL3909491 0.85 ALOX15 (0.52) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL824520 0.83 ALOX15 (0.67) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL29395805 0.83 ALOX15 (0.67) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL8042625 0.83 ALDH1A1 (0.50) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL27515308 0.81 ALOX15 (0.64) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL866395 0.79 ALOX15 (0.61) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL30747043 0.79 ALOX15 (0.61) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL5024851 0.79 ALOX15 (0.50) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112852057-A Anti-aging improved polypropylene composition and preparation method thereof 安特普工程塑料(苏州)有限公司 2021-05-28 CN claimed
US-20090163692-A1 AROMATIC POLYETHERS GENERAL ELECTRIC COMPANY (US) 2009-06-25 US claimed
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP claimed
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
CN-112852057-A Anti-aging improved polypropylene composition and preparation method thereof 安特普工程塑料(苏州)有限公司 2021-05-28 CN disclosed
US-10428216-B2 Golf ball incorporating a mixture of a thermoset and/or thermoplastic composition and a plurality of conductive nanoshelled structures ACUSHNET COMPANY (US) 2019-10-01 US disclosed
US-20190192922-A1 GOLF BALL COMPRISING MEDIUM HARDNESS GRADIENT CORE ACUSHNET COMPANY (US) 2019-06-27 US disclosed
US-10252115-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2019-04-09 US disclosed
US-10220263-B2 Golf balls comprising medium hardness gradient core ACUSHNET COMPANY (US) 2019-03-05 US disclosed
US-10130848-B2 Golf ball multilayer core having a gradient quotient ACUSHNET COMPANY (US) 2018-11-20 US disclosed
US-20180318654-A1 GOLF BALL INCORPORATING POSITIVE HARDNESS GRADIENT THERMOSET POLYURETHANE OUTER COVER LAYER ACUSHNET COMPANY (US) 2018-11-08 US disclosed
US-3966711-A 4-Alkyl-1,4-diaza-5-oxo-cycloheptanes and their 1-oxyls CIBA-GEIGY CORPORATION (US) 1976-06-29 US disclosed
US-3959326-A COMPLEXES WITH PHOSPHATE, CARBOXYLIC ACID, ALKALI METAL CIBA-GEIGY CORPORATION (US) 1976-05-25 US disclosed
US-3948852-A Nickel stabilisers for synthetic polymers CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed
US-3943098-A 1-Aza-4-thiacyclohexane-4,4-dioxide derivatives and their use as agents protecting against light rays CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3943106-A POLYESTERS AND POLYAMIDS FROM HYDROXYBENZYLMALONIC ACID DERIVATIVES; STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3940363-A POLYMERS SANKYO COMPANY LIMITED (JA) 1976-02-24 US disclosed
US-3939175-A STABILIZER CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed