Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.50 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 5/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.48 |
| ▸ | GSK3B | P49841 | 4/20 | 0.48 |
| ▸ | CSNK1G2 | P78368 | 4/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381841 | 0.88 | GRIN1 (0.55) | GRIN1GRIN2BPIN1KMT2APOLB | |
| SCHEMBL7655135 | 0.85 | RAD52 (0.61) | GRIN1GRIN2BPIN1KMT2APOLB | |
| SCHEMBL3391734 | 0.81 | GRIN1 (0.55) | GRIN1GRIN2BPIN1KMT2APOLB | |
| SCHEMBL7653726 | 0.81 | TDP1 (0.59) | GRIN1GRIN2BPIN1KMT2APOLB | |
| SCHEMBL7653331 | 0.81 | GRIN1 (0.53) | GRIN1GRIN2BPIN1KMT2APOLB | |
| SCHEMBL8387327 | 0.79 | GRIN1 (0.46) | GRIN1GRIN2BPIN1KMT2APOLB | |
| SCHEMBL4069591 | 0.77 | PIN1 (0.63) | GRIN1GRIN2BPIN1PKN1PKN2 | |
| SCHEMBL7659965 | 0.76 | HTT (0.63) | GRIN1GRIN2BPIN1KMT2APOLB | |
| SCHEMBL1245514 | 0.76 | PIN1 (0.58) | GRIN1GRIN2BPIN1PKN1PKN2 | |
| SCHEMBL485969 | 0.75 | GRIN1 (0.43) | GRIN1GRIN2BPIN1KMT2APKN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200331847-A1 | ALPHA-CINNAMIDE COMPOUNDS AND COMPOSITIONS AS HDAC8 INHIBITORS | VALO HEALTH, INC. | 2020-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331847-A1 | ALPHA-CINNAMIDE COMPOUNDS AND COMPOSITIONS AS HDAC8 INHIBITORS | HDAC8, HDAC7, HDAC1 | GRIN1 1509/4885GRIN2B 3110/4885PIN1 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.