Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 4/20 | 0.35 |
| ▸ | BID | P55957 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | LYN | P07948 | 2/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453096 | 0.87 | NPC1 (0.51) | NPC1LMNARAB9AMEN1KMT2A | |
| SCHEMBL21587013 | 0.82 | NPC1 (0.46) | NPC1LMNARAB9AMEN1KMT2A | |
| SCHEMBL11418479 | 0.76 | NPC1 (0.51) | NPC1LMNARAB9AMEN1KMT2A | |
| SCHEMBL14017581 | 0.76 | NPC1 (0.43) | NPC1LMNARAB9AMEN1KMT2A | |
| SCHEMBL25409485 | 0.75 | NPC1 (0.36) | NPC1LMNARAB9AMEN1KMT2A | |
| SCHEMBL30130370 | 0.73 | NPC1 (0.69) | NPC1LMNARAB9AMEN1KMT2A | |
| SCHEMBL698631 | 0.73 | NPC1 (0.69) | NPC1LMNARAB9AMEN1KMT2A | |
| SCHEMBL5072336 | 0.72 | MEN1 (0.36) | NPC1LMNARAB9AMEN1KMT2A | |
| SCHEMBL9868355 | 0.72 | MYC (0.46) | NPC1LMNARAB9AMEN1KMT2A | |
| SCHEMBL28260891 | 0.72 | KDM6B (0.38) | NPC1LMNARAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11359031-B2 | Composition for ophthalmological products | Johnson & Johnson Surgical Vision, Inc. (US) | 2022-06-14 | — | — | US | disclosed |
| US-20200332041-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | MERCK PATENT GMBH (DE) | 2020-10-22 | — | — | US | disclosed |
| CN-105792860-B | Reflective soft acrylic material with high refractive index and minimum | 诺华股份有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-107206123-A | Wet packed intraocular lens material with high refractive index | 诺华股份有限公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-105793303-B | Soft hydrophobic acrylic materials | 诺华股份有限公司 | 2017-08-29 | — | — | CN | disclosed |