Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22554447 | 0.87 | NPC1 (0.38) | NPC1RAB9ALMNABRD4CCNK | |
| SCHEMBL27547302 | 0.75 | NPC1 (0.54) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| Acetic Acid SCHEMBL6571740 | 0.74 | NPC1 (0.56) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29566424 | 0.73 | NPC1 (0.51) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL299318 | 0.73 | NPC1 (0.51) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11609812 | 0.73 | NPC1 (0.58) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6535795 | 0.72 | NPC1 (0.48) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL251422 | 0.72 | NPC1 (0.61) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11611277 | 0.72 | NPC1 (0.57) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7160226 | 0.71 | NPC1 (0.49) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1256611-B1 | Aqueous dispersion and coated product | JSR CORP (JP) | 2009-07-29 | — | — | EP | disclosed |
| US-20030073779-A1 | Aqueous dispersion and coated product | JSR CORPORATION (JP) | 2003-04-17 | — | — | US | disclosed |
| EP-1256611-A2 | Aqueous dispersion and coated product | JSR Corporation (JP) | 2002-11-13 | — | — | EP | disclosed |