SCHEMBL9868355

SCHEMBL9868355

O=C(O)c1ccc(O)c(-n2nc3ccc(Cl)cc3n2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.46
CDH1 P12830 1/20 0.43
APC P25054 1/20 0.43
CTNNB1 P35222 1/20 0.43
TCF7L2 Q9NQB0 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
LMNA P02545 2/20 0.42
TTR P02766 3/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
POLB P06746 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 2/20 0.41
GAA P10253 2/20 0.41
CA12 O43570 1/20 0.41
MAPT P10636 1/20 0.41
CA4 P22748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2401376 0.90 MYC (0.51) MYCCDH1APCCTNNB1TCF7L2
SCHEMBL11418479 0.85 NPC1 (0.51) MEN1KMT2ANPC1RAB9ALMNA
SCHEMBL31309385 0.84 NPC1 (0.59) MYCMEN1KMT2ANPC1RAB9A
SCHEMBL2797053 0.84 NPC1 (0.59) MYCMEN1KMT2ANPC1RAB9A
SCHEMBL9868064 0.83 MYC (0.41) MYCCDH1APCCTNNB1TCF7L2
SCHEMBL9867903 0.82 MYC (0.42) MYCCDH1APCCTNNB1TCF7L2
SCHEMBL9868134 0.81 CA1 (0.40) MYCCDH1APCCTNNB1TCF7L2
SCHEMBL1703022 0.81 RAB9A (0.64) MYCMEN1KMT2ANPC1RAB9A
SCHEMBL8642652 0.80 CA2 (0.49) MEN1KMT2ANPC1RAB9ALMNA
SCHEMBL18928204 0.80 KDM4E (0.44) MYCMEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5071995-A Excellent ultraviolet absorbability for polyesters and polyamides; high thermal stability KURARAY CO., LTD. (JP) 1991-12-10 US disclosed
EP-0363839-A1 2-hydroxyphenylbenzotriazol compounds and the use thereof KURARAY CO., LTD. (JP) 1990-04-18 EP disclosed