Pyridine

Pyridine

SCHEMBL2255454

O=S(=O)(O)OS(=O)(=O)O.c1ccncc1.c1ccncc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 0.47
TSHR P16473 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CA2 P00918 1/20 0.32
GRIN1 Q05586 5/20 0.31
GRIN2B Q13224 5/20 0.31
GRIN2D O15399 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2C Q14957 1/20 0.31
MAPT P10636 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL9785253 1.00 NAPRT (0.47) NAPRTTSHRTDP1CA2GRIN1
Pyridine SCHEMBL22261991 0.88 NAPRT (0.41) NAPRTTSHRTDP1
Pyridine SCHEMBL8873439 0.87 NAPRT (0.36) NAPRTTSHRTDP1GRIN1GRIN2B
Pyridine SCHEMBL2424840 0.84 NAPRT (0.38) NAPRTTSHRTDP1
Pyridine SCHEMBL28257184 0.84 CA2 (0.53) NAPRTTSHRTDP1CA2GRIN1
Pyridine SCHEMBL2424842 0.84 CA2 (0.53) NAPRTTSHRTDP1CA2GRIN1
Pyrimidine SCHEMBL21056189 0.84 NAPRT (0.37) NAPRTCA2
Pyridine SCHEMBL984983 0.83 TSHR (0.53) NAPRTTSHRTDP1GRIN1GRIN2B
Pyridine SCHEMBL22261964 0.83 NAPRT (0.60) NAPRTTSHRTDP1MAPTMEN1
Pyridine SCHEMBL22261990 0.83 NAPRT (0.60) NAPRTTSHRTDP1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116063360-A Disaccharide polysulfate for improving skin function, and preparation method and application thereof 麦吉丽生物科技有限公司 2023-05-05 CN claimed
US-9394378-B2 Process for obtaining chondroitin sulphated at the 4- or 6- positions of N-acetyl-galactosamine residues ALTERGON S.A. (CH) 2016-07-19 US claimed
CN-103298837-B Obtain the method at the Sulfated chrondroitin in 4-or 6-position of GalNAc residue ALTERGON S.A. (CH) 2016-01-20 CN claimed
EP-2638074-B1 PROCESS FOR OBTAINING CHONDROITIN SULPHATED AT THE 4- OR 6- POSITIONS OF N-ACETYL-GALACTOSAMINE RESIDUES ALTERGON SA (CH) 2015-01-07 EP claimed
EP-2638074-A2 PROCESS FOR OBTAINING CHONDROITIN SULPHATED AT THE 4- OR 6- POSITIONS OF N-ACETYL-GALACTOSAMINE RESIDUES Altergon S.a. (CH) 2013-09-18 EP claimed
CN-103298837-A Process for obtaining chondroitin sulphated at the 4- or 6- positions of n-acetyl-galactosamine residues ALTERGON SA 2013-09-11 CN claimed
US-20130225802-A1 PROCESS FOR OBTAINING CHONDROITIN SULPHATED AT THE 4- OR 6- POSITIONS OF N-ACETYL-GALACTOSAMINE RESIDUES ALTERGON S.A. (CH) 2013-08-29 US claimed
WO-2012062917-A2 PROCESS FOR OBTAINING CHONDROITIN SULPHATED AT THE 4- OR 6- POSITIONS OF N-ACETYL-GALACTOSAMINE RESIDUES ALTERGON S.A. (CH) 2012-05-18 WO claimed
US-20050203056-A1 Carboxyl-reduced derivatives of hyaluronic acid, preparation thereof, use thereof as a medicinal product and the pharmaceutical compositions containing them AVENTIS PHARMA S.A. (FR) 2005-09-15 US claimed
US-20050187187-A1 Carboxyl-reduced derivatives of chondroitin sulfate, preparation thereof, use thereof as a medicinal product and the pharmaceutical compositions containing them AVENTIS PHARMAS S.A. (FR) 2005-08-25 US claimed
US-20050164983-A1 Carboxyl-reduced derivatives of dermatan sulfate, preparation thereof, use thereof as a medicinal product and the pharmaceutical compositions containing them AVENTIS PHARMA S.A. (FR) 2005-07-28 US claimed
WO-2003066657-A1 A PROCESS FOR PREPARING URSODEOXYCHOLIC ACID DUSULPHATE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF ABC INTERNATIONAL PHARMA S.R.L. (IT) 2003-08-14 WO claimed
US-5254681-A Process for preparing monobactames and their intermediate product CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1993-10-19 US claimed
EP-0411541-A2 Process for preparing monobactames and their intermediate product CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1991-02-06 EP claimed
EP-0159026-B1 PENTAERYTHRITOL DERIVATIVES AND A PROCESS FOR PREPARING THE SAME Chugai Seiyaku Kabushiki Kaisha (JP) 1988-08-24 EP claimed
EP-0107860-B1 PEPTIDES, PROCESS FOR PREPARING THE SAME AND PSYCHODEPRESSANT COMPOSITIONS CONTAINING THE SAME AMANO PHARMACEUTICAL CO., LTD. (JP) 1986-09-17 EP claimed
US-4565811-A Sodium salt of ursodeoxycholic sulphate ISTITUTO BIOLOGICO CHEMIOTERAPICO "ABC" S.P.A. (IT) 1986-01-21 US claimed
EP-0159026-A2 Pentaerythritol derivatives and a process for preparing the same Chugai Seiyaku Kabushiki Kaisha (JP) 1985-10-23 EP claimed
EP-0117570-A1 Sodium salt of ursodeoxycholic sulphate ISTITUTO BIOLOGICO CHEMIOTERAPICO "ABC" S.p.A. (IT) 1984-09-05 EP claimed
EP-0107860-A1 Peptides, process for preparing the same and psychodepressant compositions containing the same AMANO PHARMACEUTICAL CO., LTD. (JP) 1984-05-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050203056-A1 Carboxyl-reduced derivatives of hyaluronic acid, preparation thereof, use thereof as a medicinal product and the pharmaceutical compositions containing them CD44, H1-3, H1-0 NAPRT 1563/4885TSHR 2065/4885TDP1 4620/4885
US-20050164983-A1 Carboxyl-reduced derivatives of dermatan sulfate, preparation thereof, use thereof as a medicinal product and the pharmaceutical compositions containing them ACMSD, C1S, C1R NAPRT 2343/4885TSHR 4266/4885TDP1 4729/4885
US-20050187187-A1 Carboxyl-reduced derivatives of chondroitin sulfate, preparation thereof, use thereof as a medicinal product and the pharmaceutical compositions containing them C1S, CSGALNACT1, CS NAPRT 1587/4885TSHR 4304/4885TDP1 4839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.