SCHEMBL22556862

SCHEMBL22556862

O=CC(=O)COP(=O)(O)O

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TPI1 P60174 2/20 0.48
MPI P34949 1/20 0.39
PGK1 P00558 1/20 0.37
PGK2 P07205 1/20 0.37
PGD P52209 2/20 0.34
LPAR3 Q9UBY5 5/20 0.33
LPAR2 Q9HBW0 3/20 0.33
LPAR1 Q92633 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1975327 0.78 TPI1 (0.46) TPI1MPIPGK1PGK2PGD
SCHEMBL5485133 0.73 TPI1 (0.56) TPI1PGK1PGK2PGDLPAR3
SCHEMBL420143 0.71 TPI1 (0.45) TPI1MPIPGK1PGK2PGD
Phosphoglycolic Acid SCHEMBL380471 0.70
Phosphoglycolic Acid SCHEMBL20798069 0.70 TPI1 (0.54) TPI1PGK1PGK2PGDLPAR3
Methylglyoxal SCHEMBL20913196 0.70 TPI1 (0.39) TPI1MPIPGK1PGK2LPAR3
SCHEMBL28691297 0.69
Phosphoglycolic Acid SCHEMBL29156120 0.69 TPI1 (0.52) TPI1PGK1PGK2PGD
Phosphoglycolic Acid SCHEMBL5586781 0.69 TPI1 (0.52) TPI1PGK1PGK2PGDLPAR3
SCHEMBL2699376 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020212453-A1 NEW PROCESS FOR MULTIPLE ALDOL REACTIONS UNIVERSITE CLERMONT AUVERGNE (FR) 2020-10-22 WO disclosed