SCHEMBL420143

SCHEMBL420143

O=CCC(=O)COP(=O)(O)O

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TPI1 P60174 2/20 0.45
MPI P34949 1/20 0.36
PGK1 P00558 1/20 0.34
PGK2 P07205 1/20 0.34
PGD P52209 2/20 0.32
LPAR3 Q9UBY5 4/20 0.31
LPAR2 Q9HBW0 3/20 0.31
LPAR1 Q92633 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5485133 0.80 TPI1 (0.56) TPI1PGK1PGK2PGDLPAR3
SCHEMBL2474974 0.73 TPI1 (0.50) TPI1PGK1PGK2PGDLPAR3
SCHEMBL43277 0.73 TPI1 (0.50) TPI1PGK1PGK2PGDLPAR3
SCHEMBL29156118 0.71 TPI1 (0.48) TPI1PGK1PGK2PGDLPAR3
SCHEMBL28769882 0.71 TPI1 (0.48) TPI1PGK1PGK2PGDLPAR3
SCHEMBL7059626 0.71 TPI1 (0.48) TPI1PGK1PGK2PGDLPAR3
SCHEMBL28466527 0.71 TPI1 (0.48) TPI1PGK1PGK2PGDLPAR3
Water SCHEMBL28701484 0.71 TPI1 (0.48) TPI1PGK1PGK2PGDLPAR3
SCHEMBL22556862 0.71 TPI1 (0.48) TPI1MPIPGK1PGK2PGD
SCHEMBL1065797 0.71 TPI1 (0.48) TPI1PGK1PGK2PGDLPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103025877-A Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene GENOMATICA INC 2013-04-03 CN claimed
US-20220056488-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE GENOMATICA INC (US) 2022-02-24 US disclosed
US-10793882-B2 Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene GENOMATICA, INC. (US) 2020-10-06 US disclosed
EP-3312284-A2 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE Genomatica, Inc. (US) 2018-04-25 EP disclosed
US-20170335352-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE AGAIN BIO APS (DK) 2017-11-23 US disclosed
EP-2607340-B1 Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene GENOMATICA INC (US) 2017-09-06 EP disclosed
US-9556461-B2 Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene GENOMATICA, INC. (US) 2017-01-31 US disclosed
US-20150064750-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE GENOMATICA, INC. (US) 2015-03-05 US disclosed
US-8715957-B2 Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene GENOMATICA, INC. (US) 2014-05-06 US disclosed
EP-2607340-A1 Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene Genomatica, Inc. (US) 2013-06-26 EP disclosed
CN-103025877-A Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene GENOMATICA INC 2013-04-03 CN disclosed
WO-2012018624-A2 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE GENOMATICA, INC. (US) 2012-02-09 WO disclosed
US-20120021478-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE AGAIN BIO APS (DK) 2012-01-26 US disclosed