Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168238 | 0.87 | — | — | |
| Phosphoric Acid SCHEMBL16965610 | 0.74 | ALDH1A1 (0.43) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| Glycolic Acid SCHEMBL27598096 | 0.67 | TSHR (0.50) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| Dihydroxyacetone SCHEMBL43279 | 0.67 | KDM4E (0.35) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| Glycolic Acid SCHEMBL3928196 | 0.67 | TSHR (0.50) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| Phosphoric Acid SCHEMBL6565378 | 0.67 | — | — | |
| Dihydroxyacetone SCHEMBL20798012 | 0.67 | KDM4E (0.35) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL5308018 | 0.66 | — | — | |
| Methylglyoxal SCHEMBL14244241 | 0.65 | ALDH1A1 (0.39) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| Dihydroxyacetone SCHEMBL290997 | 0.65 | KDM4E (0.33) | KDM4EMMP2THRBMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020212453-A1 | NEW PROCESS FOR MULTIPLE ALDOL REACTIONS | UNIVERSITE CLERMONT AUVERGNE (FR) | 2020-10-22 | — | — | WO | disclosed |