Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | PLAU | P00749 | 3/20 | 0.50 |
| ▸ | ELANE | P08246 | 3/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28677098 | 0.86 | MAPT (0.50) | F2PLAUELANEALDH1A1GAA | |
| SCHEMBL29099930 | 0.82 | L3MBTL1 (0.43) | F2PLAUELANEALDH1A1LMNA | |
| SCHEMBL22557510 | 0.79 | MYC (0.50) | MYCALDH1A1LMNAGAACYP2C19 | |
| SCHEMBL22632956 | 0.79 | MEN1 (0.56) | F2PLAUELANEALDH1A1LMNA | |
| SCHEMBL22633304 | 0.76 | F2 (0.55) | F2PLAUELANEALDH1A1LMNA | |
| SCHEMBL25011687 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTKDM4EHTT | |
| SCHEMBL21050103 | 0.76 | ALDH1A1 (0.50) | F2PLAUELANEALDH1A1LMNA | |
| SCHEMBL26696901 | 0.75 | RXFP1 (0.43) | F2PLAUELANEALDH1A1LMNA | |
| SCHEMBL28542620 | 0.74 | MYC (0.46) | F2PLAUELANEMYCALDH1A1 | |
| SCHEMBL26696807 | 0.74 | F2 (0.46) | F2PLAUELANEALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710664-B | JAK1 selective kinase inhibitors | 迪哲(江苏)医药股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| EP-3956322-A1 | JAK1 SELECTIVE KINASE INHIBITOR | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2022-02-23 | — | — | EP | disclosed |
| WO-2020211839-A1 | JAK1 SELECTIVE KINASE INHIBITOR | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2020-10-22 | — | — | WO | disclosed |