Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26696930 | 0.79 | CA12 (0.42) | RXFP1L3MBTL1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL26696707 | 0.79 | MAPT (0.43) | RXFP1L3MBTL1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL2061145 | 0.75 | NPC1 (0.54) | L3MBTL1KCNA5CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL19268475 | 0.75 | LMNA (0.53) | GAACYP2C9CYP2C19SMN1; SMN2MAPT | |
| SCHEMBL20278290 | 0.75 | ALDH1A1 (0.42) | GAACYP2C19SMN1; SMN2MAPTRAB9A | |
| SCHEMBL22556864 | 0.75 | F2 (0.50) | RXFP1L3MBTL1GAACYP2C9CYP2C19 | |
| SCHEMBL14907666 | 0.74 | MGLL (0.54) | RXFP1KCNA5GAACYP2C9CYP2C19 | |
| SCHEMBL26697059 | 0.74 | F2 (0.43) | RXFP1L3MBTL1GAACYP2C9CYP2C19 | |
| SCHEMBL3654246 | 0.74 | CA1 (0.52) | L3MBTL1KCNA5HDAC10HDAC6CA12 | |
| SCHEMBL3656591 | 0.74 | CA1 (0.44) | KCNA5HDAC10HDAC6CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227125-A1 | NEW FUSED-HETEROCYCLIC COMPOUND AS CDK INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |