Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22556956 | 1.00 | CA14 (0.37) | CA14SMN1; SMN2CHRNB2CHRNA4CA12 | |
| SCHEMBL28012693 | 0.84 | SLC7A5 (0.39) | SMN1; SMN2 | |
| SCHEMBL28660296 | 0.82 | CA14 (0.37) | CA14SMN1; SMN2CHRNB2CHRNA4CA12 | |
| SCHEMBL238192 | 0.82 | — | — | |
| SCHEMBL709174 | 0.82 | — | — | |
| SCHEMBL801212 | 0.82 | — | — | |
| SCHEMBL7902793 | 0.81 | ALDH1A1 (0.37) | — | |
| SCHEMBL15741912 | 0.81 | SLC1A3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL3943090 | 0.80 | — | — | |
| SCHEMBL3457292 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710674-B | Diastereoselective process for preparing maytansinoids containing thiols or disulfides and intermediates thereof | 意迪那有限公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-3956332-B1 | DIASTEROSELECTIVE PROCESS FOR THE PREPARATION OF THIOL- OR DISULFIDE-CONTAINING MAYTANSINOID ESTERS AND INTERMEDIATES THEREOF | INDENA SPA (IT) | 2023-02-22 | — | — | EP | disclosed |
| US-11420981-B2 | Diasteroselective process for the preparation of thiol- or disulfide-containing maytansinoid esters and intermediates thereof | INDENA S.P.A. (IT) | 2022-08-23 | — | — | US | disclosed |
| US-20220119408-A1 | DIASTEROSELECTIVE PROCESS FOR THE PREPARATION OF THIOL- OR DISULFIDE-CONTAINING MAYTANSINOID ESTERS AND INTERMEDIATES THEREOF | INDENA S.P.A. (IT) | 2022-04-21 | — | — | US | disclosed |
| EP-3956332-A1 | DIASTEROSELECTIVE PROCESS FOR THE PREPARATION OF THIOL- OR DISULFIDE-CONTAINING MAYTANSINOID ESTERS AND INTERMEDIATES THEREOF | Indena S.p.A. (IT) | 2022-02-23 | — | — | EP | disclosed |
| CN-113710674-A | Diastereoselective process for preparing thiol-or disulfide-containing maytansinoids and intermediates thereof | 因德纳有限公司 | 2021-11-26 | — | — | CN | disclosed |
| WO-2020212256-A1 | DIASTEROSELECTIVE PROCESS FOR THE PREPARATION OF THIOL- OR DISULFIDE-CONTAINING MAYTANSINOID ESTERS AND INTERMEDIATES THEREOF | INDENA S.P.A. (IT) | 2020-10-22 | — | — | WO | disclosed |
| CN-1112932-A | Lactic acid-containing cyclic depsipeptides with 18 ring atoms as endoparasiticides and process for their preparation | BAYER AG (DE) | 1995-12-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119408-A1 | DIASTEROSELECTIVE PROCESS FOR THE PREPARATION OF THIOL- OR DISULFIDE-CONTAINING MAYTANSINOID ESTERS AND INTERMEDIATES THEREOF | STS, SRR, SPR | CA14 1053/4885SMN1; SMN2 3974/4885CHRNB2 2427/4885 |
| US-11420981-B2 | Diasteroselective process for the preparation of thiol- or disulfide-containing maytansinoid esters and intermediates thereof | STS, SRR, SPR | CA14 1053/4885SMN1; SMN2 3974/4885CHRNB2 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.