Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2253092 | 0.94 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL13250567 | 0.83 | ALDH1A1 (0.39) | SIGMAR1 | |
| SCHEMBL1002592 | 0.80 | ALDH1A1 (0.39) | SIGMAR1 | |
| SCHEMBL13250560 | 0.80 | ALDH1A1 (0.37) | SIGMAR1 | |
| SCHEMBL2254250 | 0.80 | ALDH1A1 (0.30) | — | |
| SCHEMBL2253368 | 0.80 | MCL1 (0.47) | SIGMAR1 | |
| SCHEMBL297631 | 0.79 | KDM4E (0.31) | SIGMAR1 | |
| SCHEMBL24054459 | 0.79 | ALDH1A1 (0.38) | SIGMAR1 | |
| SCHEMBL27681984 | 0.77 | ALDH1A1 (0.41) | SIGMAR1 | |
| SCHEMBL2251174 | 0.76 | SIGMAR1 (0.33) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1916244-B1 | THIOPHENE COMPOUND HAVING SULFONYL GROUP AND PROCESS FOR PRODUCING THE SAME | NISSAN CHEMICAL IND LTD (JP) | 2013-12-04 | — | — | EP | disclosed |
| EP-1882694-B1 | OLIGOMERS AND POLYMERS OF THIOPHENE COMPOUNDS HAVING PHOSPHORIC ESTER AND PROCESS FOR PRODUCING THE SAME | NISSAN CHEMICAL IND LTD (JP) | 2013-04-03 | — | — | EP | disclosed |
| US-8008425-B2 | Thiophene compound having sulfonyl group and process for producing the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-08-30 | — | — | US | disclosed |
| US-20090127491-A1 | THIOPHENE COMPOUND HAVING SULFONYL GROUP AND PROCESS FOR PRODUCING THE SAME | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-1916244-A1 | THIOPHENE COMPOUND HAVING SULFONYL GROUP AND PROCESS FOR PRODUCING THE SAME | Nissan Chemical Industries, Ltd. (JP) | 2008-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090127491-A1 | THIOPHENE COMPOUND HAVING SULFONYL GROUP AND PROCESS FOR PRODUCING THE SAME | TST, ABCG2, CBR3 | SIGMAR1 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.