Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30277616 | 0.79 | TP53BP1 (0.67) | L3MBTL1SMN1; SMN2ALDH1A1POLBTP53BP1 | |
| SCHEMBL104557 | 0.79 | TP53BP1 (0.67) | L3MBTL1SMN1; SMN2ALDH1A1POLBTP53BP1 | |
| SCHEMBL12829992 | 0.78 | L3MBTL1 (0.63) | L3MBTL1SMN1; SMN2ALDH1A1POLBTP53BP1 | |
| SCHEMBL13763531 | 0.77 | L3MBTL1 (0.80) | L3MBTL1SMN1; SMN2ALDH1A1POLBTP53BP1 | |
| SCHEMBL18599247 | 0.77 | TERT (0.44) | L3MBTL1SMN1; SMN2ALDH1A1POLBTP53BP1 | |
| SCHEMBL12303198 | 0.76 | TERT (0.49) | L3MBTL1SMN1; SMN2TP53BP1GAAGPR139 | |
| SCHEMBL19062131 | 0.76 | TERT (0.49) | L3MBTL1SMN1; SMN2TP53BP1GAAGPR139 | |
| SCHEMBL12988864 | 0.75 | L3MBTL1 (0.63) | L3MBTL1SMN1; SMN2ALDH1A1POLBERN1 | |
| SCHEMBL17658901 | 0.75 | TP53BP1 (0.61) | L3MBTL1SMN1; SMN2TP53BP1NPC1RAB9A | |
| SCHEMBL8737487 | 0.74 | TP53BP1 (0.46) | L3MBTL1SMN1; SMN2TP53BP1GAAGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020212697-A1 | INHIBITOR COMPOUNDS | Azeria Therapeutics Limited (GB) | 2020-10-22 | — | — | WO | disclosed |
| WO-2020212697-A1 | INHIBITOR COMPOUNDS | Azeria Therapeutics Limited (GB) | 2020-10-22 | — | — | WO | disclosed |