Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.41 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.41 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552180 | 0.81 | LMNA (0.51) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL22561017 | 0.80 | SRD5A2 (0.43) | KDM4EMAPTHPGDCYP1A2CYP2D6 | |
| SCHEMBL22561163 | 0.77 | BACE1 (0.50) | KDM4EALDH1A1MAPTHPGDPLAU | |
| SCHEMBL22459866 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTHPGDPLAU | |
| SCHEMBL22459418 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTHPGDPLAU | |
| SCHEMBL22561116 | 0.76 | CYP17A1 (0.49) | ALDH1A1ERN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL22561133 | 0.76 | EGFR (0.36) | KDM4EEGFRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17599105 | 0.72 | CYP1A1 (0.71) | KDM4EALDH1A1PLAUCYP1A2CYP3A4 | |
| SCHEMBL22561015 | 0.71 | ESR1 (0.40) | EGFRERN1ESR1ESR2 | |
| SCHEMBL19854405 | 0.71 | BACE1 (0.52) | KDM4EALDH1A1MAPTHPGDPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725764-A1 | POLYMERIZABLE COMPOUND HAVING METHOXYMETHYL ACRYLIC GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC Corporation (JP) | 2020-10-21 | — | — | EP | disclosed |