Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143358 | 0.91 | HRH3 (0.45) | HRH3CXCR4ALOX15HIF1AEPAS1 | |
| SCHEMBL21550453 | 0.80 | HRH3 (0.43) | HRH3DGAT1 | |
| SCHEMBL1485000 | 0.79 | HRH3 (0.42) | HRH3KCNH2DGAT1 | |
| SCHEMBL30434278 | 0.78 | LTA4H (0.39) | HRH3DGAT1 | |
| SCHEMBL15647594 | 0.78 | LTA4H (0.39) | HRH3DGAT1 | |
| SCHEMBL12314740 | 0.77 | HRH3 (0.41) | HRH3CXCR4ALOX15HIF1AEPAS1 | |
| SCHEMBL15648977 | 0.77 | DGAT1 (0.40) | CXCR4DGAT1 | |
| SCHEMBL30889384 | 0.77 | DGAT1 (0.40) | CXCR4DGAT1 | |
| SCHEMBL22561593 | 0.74 | DGAT1 (0.38) | HRH3DGAT1 | |
| SCHEMBL34471611 | 0.74 | DGAT1 (0.37) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725314-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2020-10-21 | — | — | EP | disclosed |