Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.38 |
| ▸ | LPL | P06858 | 3/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PAICS | P22234 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15647594 | 1.00 | LTA4H (0.39) | LTA4HDGAT1LPLLIPGHRH3 | |
| SCHEMBL21550453 | 0.89 | HRH3 (0.43) | DGAT1LPLLIPGHRH3USP30 | |
| SCHEMBL143358 | 0.87 | HRH3 (0.45) | DGAT1LPLLIPGHRH3 | |
| SCHEMBL30889384 | 0.86 | DGAT1 (0.40) | DGAT1LPLLIPGPAICSUSP30 | |
| SCHEMBL15648977 | 0.86 | DGAT1 (0.40) | DGAT1LPLLIPGPAICSUSP30 | |
| SCHEMBL22561593 | 0.85 | DGAT1 (0.38) | DGAT1LPLLIPGHRH3USP30 | |
| SCHEMBL17136271 | 0.84 | DGAT1 (0.42) | DGAT1HRH3KDM4EUSP30 | |
| SCHEMBL24092596 | 0.81 | KDM4E (0.37) | LTA4HLPLLIPGMC4RKDM4E | |
| SCHEMBL34471611 | 0.80 | DGAT1 (0.37) | DGAT1LPLLIPGUSP30 | |
| SCHEMBL429722 | 0.79 | LMNA (0.53) | LPLLIPGMC4RKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444714-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PI3KALPHA INHIBITORS | Nanjing Zenshine Pharmaceuticals Co., Ltd. (CN) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023104111-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PI3KALPHA INHIBITORS | NANJING ZENSHINE PHARMACEUTICALS CO., LTD. (CN) | 2023-06-15 | — | — | WO | disclosed |