Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 10/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL763088 | 0.73 | ALDH1A1 (0.48) | ALDH1A1THRBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL18184682 | 0.73 | ALDH1A1 (0.63) | ALDH1A1THRBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL3205606 | 0.70 | HSD17B10 (0.50) | ALDH1A1THRBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL22538967 | 0.69 | NNMT (0.42) | MAPTSMN1; SMN2NPC1KDM4EMEN1 | |
| SCHEMBL478161 | 0.68 | THRB (0.44) | ALDH1A1THRBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL16859020 | 0.67 | THRB (0.44) | ALDH1A1THRBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL30443271 | 0.67 | KMT2A (0.53) | ALDH1A1NPC1RAB9AMEN1LMNA | |
| SCHEMBL11955066 | 0.66 | ALDH1A1 (0.44) | ALDH1A1THRBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL12640261 | 0.64 | MAPT (0.71) | ALDH1A1THRBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL8828774 | 0.64 | CNR1 (0.43) | ALDH1A1THRBMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725785-A1 | GLUTARIMIDE DERIVATIVES, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHODS FOR PRODUCING GLUTARIMIDE DERIVATIVES | Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) | 2020-10-21 | — | — | EP | disclosed |